MOFs and MOF-Based Composites as Next-Generation Materials for Wound Healing and Dressings

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dc.authoridIravani, Siavash/0000-0003-3985-7928
dc.authorwosidIravani, Siavash/F-4046-2014
dc.contributor.authorBigham, Ashkan
dc.contributor.authorIslami, Negar
dc.contributor.authorKhosravi, Arezoo
dc.contributor.authorZarepour, Atefeh
dc.contributor.authorIravani, Siavash
dc.contributor.authorZarrabi, Ali
dc.date.accessioned2024-05-19T14:38:53Z
dc.date.available2024-05-19T14:38:53Z
dc.date.issued2024
dc.departmentİstinye Üniversitesien_US
dc.description.abstractIn recent years, there has been growing interest in developing innovative materials and therapeutic strategies to enhance wound healing outcomes, especially for chronic wounds and antimicrobial resistance. Metal-organic frameworks (MOFs) represent a promising class of materials for next-generation wound healing and dressings. Their high surface area, pore structures, stimuli-responsiveness, antibacterial properties, biocompatibility, and potential for combination therapies make them suitable for complex wound care challenges. MOF-based composites promote cell proliferation, angiogenesis, and matrix synthesis, acting as carriers for bioactive molecules and promoting tissue regeneration. They also have stimuli-responsivity, enabling photothermal therapies for skin cancer and infections. Herein, a critical analysis of the current state of research on MOFs and MOF-based composites for wound healing and dressings is provided, offering valuable insights into the potential applications, challenges, and future directions in this field. This literature review has targeted the multifunctionality nature of MOFs in wound-disease therapy and healing from different aspects and discussed the most recent advancements made in the field. In this context, the potential reader will find how the MOFs contributed to this field to yield more effective, functional, and innovative dressings and how they lead to the next generation of biomaterials for skin therapy and regeneration. Recent advancements pertaining to the applications of MOFs and their composites for wound healing and dressings are deliberated, with the purpose of identifying knowledge gaps, evaluating challenges, and guiding future directions in the field. imageen_US
dc.identifier.doi10.1002/smll.202311903
dc.identifier.issn1613-6810
dc.identifier.issn1613-6829
dc.identifier.pmid38453672en_US
dc.identifier.scopus2-s2.0-85186880328en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org10.1002/smll.202311903
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4640
dc.identifier.wosWOS:001177503200001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofSmallen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectAdvanced Materialsen_US
dc.subjectMof-Based Compositesen_US
dc.subjectMofsen_US
dc.subjectWound Dressingsen_US
dc.subjectWound Healingen_US
dc.titleMOFs and MOF-Based Composites as Next-Generation Materials for Wound Healing and Dressingsen_US
dc.typeReview Articleen_US

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