Dosimetric comparison of volumetric-modulated arc therapy and dynamic conformal arc therapy in three-fraction single-isocenter stereotactic radiosurgery for multiple brain metastases

Basit Öğe Kaydı
dc.authoridMerdan Fayda / 0000-0002-2800-5327
dc.authoridGörkem Türkkan / 0000-0002-9084-2599
dc.authorscopusidMerdan Fayda / 6506348846
dc.authorscopusidGörkem Türkkan / 56841633300
dc.authorwosidMerdan Fayda / GRB-5459-2022
dc.authorwosidGörkem Türkkan / E-7048-2017
dc.contributor.authorTürkkan, Görkem
dc.contributor.authorBilici, Nazlı
dc.contributor.authorSertel, Hüseyin
dc.contributor.authorTavlı, Büşra
dc.contributor.authorÖzkırım, Müge
dc.contributor.authorFayda, Merdan
dc.date.accessioned2021-12-22T10:54:40Z
dc.date.available2021-12-22T10:54:40Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAbstract OBJECTIVE The objective of the study was to compare single-isocenter volumetric-modulated arc therapy (VMAT) and dynamic conformal arc therapy (DCAT) techniques in patients who received multifraction stereotactic radiosurgery (SRS) for multiple brain metastases. METHODS Twenty-one patients who were treated with a radiation dose of 27 Gy in three fractions were replanned. Roth VMAT and DCAT plans with single isocenter were obtained for each patient. Plan quality indices, cumulative monitor unit (MU) values, maximum dose for organs at risk, and mean dose, V19.6(Gy), and V23.1(Gy) for healthy brain tissue were compared. RESULTS The conformity index (11=0.0002), gradient index (p=0.003), maximum dose for brainstem (p=0.016) and mean dose (p=0.00007), V19.6(Gy) (p=0.00006), and V23.1(Gy) (p=0.00006) values for healthy brain tissue were significantly superior in the VMAT technique, compared to DCAT technique. In addition, a trend toward significance for achieving lower maximum dose value to the optic nerves and/or pathway was observed with VMAT (11=0.073). DCAT provided significantly lower MU values (3097.14 vs. 1479.09; p=0.00006). CONCLUSION VMAT was able to provide better target conformity and lower risk of brain radionecrosis at least dosimetrically in multifraction SRS for patients with multiple brain metastases. DCAT may he chosen in patients with relatively poor performance status or low tolerance to long-lasting radiotherapy sessions.en_US
dc.identifier.citationTurkkan, G., Okumus, A., Bilici, N., Sertel, H., Tavli, B., Ozkirim, M. & Fayda, M. (2022). Dosimetric Comparison of Volumetric-Modulated Arc Therapy and Dynamic Conformal Arc Therapy in Three-fraction Single-isocenter Stereotactic Radiosurgery for Multiple Brain Metastases.en_US
dc.identifier.doi10.5505/tjo.2021.3412en_US
dc.identifier.issn1300-7467en_US
dc.identifier.scopus2-s2.0-85125879428en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.trdizinid1135791en_US
dc.identifier.urihttps://doi.org/10.5505/tjo.2021.3412
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2338
dc.identifier.wosWOS:000730244000001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorTürkkan, Görkem
dc.institutionauthorFayda, Merdan
dc.language.isoenen_US
dc.publisherKARE PUBLen_US
dc.relation.ispartofTURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDosimetric Comparisonen_US
dc.subjectDynamic Conformal Arc Therapyen_US
dc.subjectMultiple Brain Metastasesen_US
dc.subjectStereotactic Radiotherapyen_US
dc.subjectVolumetric-Modulated Arc Therapyen_US
dc.titleDosimetric comparison of volumetric-modulated arc therapy and dynamic conformal arc therapy in three-fraction single-isocenter stereotactic radiosurgery for multiple brain metastasesen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
255.pdf
Boyut:
241.56 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu