Recapitulating Antioxidant and Antibacterial Compounds into a Package for Tissue Regeneration: Dual Function Materials with Synergistic Effect

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dc.authoridRabiee, Navid/0000-0002-6945-8541
dc.authorid?????, Baolin Guo/0000-0001-6756-1441
dc.authoridGirish, Yarabahally R/0000-0001-6709-7159
dc.authoridPaiva-Santos, Ana Cláudia/0000-0003-2710-6000
dc.authoridNazarzadeh Zare, Ehsan/0000-0002-0446-4385
dc.authoridZarrabi, Ali/0000-0003-0391-1769
dc.authoridSEZEN, Serap/0000-0003-3382-6020
dc.authorwosidRabiee, Navid/K-4407-2019
dc.authorwosid?????, Baolin Guo/L-6235-2018
dc.authorwosidWang, Xiangdong/AAF-9148-2020
dc.authorwosidSANTOS, ANA/JPK-6411-2023
dc.authorwosidGirish, Yarabahally R/AAX-2783-2020
dc.authorwosidSantos, Ana/KHY-6833-2024
dc.authorwosidPaiva-Santos, Ana Cláudia/B-5780-2019
dc.contributor.authorShao, Minmin
dc.contributor.authorBigham, Ashkan
dc.contributor.authorYousefiasl, Satar
dc.contributor.authorYiu, Cynthia K. Y.
dc.contributor.authorGirish, Yarabahally R.
dc.contributor.authorGhomi, Matineh
dc.contributor.authorSharifi, Esmaeel
dc.date.accessioned2024-05-19T14:39:04Z
dc.date.available2024-05-19T14:39:04Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractOxidative damage and infection can prevent or delay tissue repair. Moreover, infection reinforces reactive oxygen species (ROS) formation, which makes the wound's condition even worse. Therefore, the need for antioxidant and antibacterial agents is felt for tissue regeneration. There are emerging up-and-coming biomaterials that recapitulate both properties into a package, offering an effective solution to turn the wound back into a healing state. In this article, the principles of antioxidant and antibacterial activity are summarized. The review starts with biological aspects, getting the readers to familiarize themselves with tissue barriers against infection. This is followed by the chemistry and mechanism of action of antioxidant and antibacterial materials (dual function). Eventually, the outlook and challenges are underlined to provide where the dual-function biomaterials are and where they are going in the future. It is expected that the present article inspires the designing of dual-function biomaterials to more advanced levels by providing the fundamentals and comparative points of view and paving the clinical way for these materials.en_US
dc.description.sponsorshipWenzhou Major Scientific and Technological Innovation Project [ZY2022010]; National Natural Science Foundation of China [82272555]; Zhejiang Provincial Natural Science Foundation of China [LGF21H060010]; Zhejiang Provincial Medical Technology Foundation of China [2022PY071]en_US
dc.description.sponsorshipAcknowledgements M.S. and A.B. contributed equally to this work. A.W. was supported by Wenzhou Major Scientific and Technological Innovation Project (ZY2022010), the National Natural Science Foundation of China (82272555), Zhejiang Provincial Natural Science Foundation of China (LGF21H060010), and Zhejiang Provincial Medical Technology Foundation of China (2022PY071).en_US
dc.identifier.doi10.1002/smll.202207057
dc.identifier.issn1613-6810
dc.identifier.issn1613-6829
dc.identifier.issue19en_US
dc.identifier.pmid36775954en_US
dc.identifier.scopus2-s2.0-85148016735en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org10.1002/smll.202207057
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4692
dc.identifier.volume19en_US
dc.identifier.wosWOS:000930343800001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofSmallen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectAntimicrobialen_US
dc.subjectAntioxidanten_US
dc.subjectNano-Architecturesen_US
dc.subjectNanoparticlesen_US
dc.subjectTissue Engineeringen_US
dc.titleRecapitulating Antioxidant and Antibacterial Compounds into a Package for Tissue Regeneration: Dual Function Materials with Synergistic Effecten_US
dc.typeReview Articleen_US

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