Distribution of ?-actinin-3 rs1815739 and angiotensin-1 converting enzyme indel polymorphisms in Turkish bodybuilders

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dc.authoridTeoman Akçay / 0000-0002-8252-7089
dc.authorscopusidTeoman Akçay / 23968688000
dc.authorwosidTeoman Akçay / AFG-8460-2022
dc.contributor.authorPolat, Tolga
dc.contributor.authorDoğan, Canan Sercan
dc.contributor.authorDoğan, Murat
dc.contributor.authorAkçay, Teoman
dc.contributor.authorUlucan, Korkut
dc.date.accessioned2020-11-04T12:20:37Z
dc.date.available2020-11-04T12:20:37Z
dc.date.issued2020en_US
dc.departmentİstinye Üniversitesi, Hastaneen_US
dc.description.abstractThe determination of the genetic profiles of successful athletes and the effects of these genetic parameters on athletic performance is gaining increasing interest. The majority of studies assessing the genetics of athletes usually analyse the most well-known genetic variations in athletes associated with the different specialties. The aim of the present study was to analyse the ACE InDel and ACTN3 rs1815739 polymorphisms in Turkish bodybuilders. A total of 11 male bodybuilders were recruited and genotyped for these polymorphisms. The respective percentage of the ACE II, ID and DD genotypes were 18, 73 and 9. For the ACTN3 genotype, the respective frequencies were 55 and 45 for the RX and RR genotypes. No XX genotype was detected. The allelic counts were 12 (55%) for I and 10 (45%) for the D alleles of ACE; and 12 (55%) and 10 (45%) for R and X alleles, respectively, for the ACTN3 genotype. Additionally, 5 athletes had ID + RX genotypes in terms of ACE InDel and ACTN3 rs1815739 polymorphisms, respectively. These results indicate the importance of endurance related alleles of ACE and ACTN3 in bodybuilders. The results of the present are in agreement with previous studies, highlighting a potential association between specific polymorphisms and the endurance-related nature of bodybuilders. Further studies with larger cohorts are required to understand the association between these polymorphisms and specific parameters performance in bodybuilders.en_US
dc.identifier.citationPolat, T., Dogan, C. S., Dogan, M., Akçay, T., & Ulucan, K. (2020). Distribution of α‑actinin‑3 rs1815739 and angiotensin‑1 converting enzyme InDel polymorphisms in Turkish bodybuilders. Biomedical Reports, 13(6), 1-1.en_US
dc.identifier.doi10.3892/br.2020.1374en_US
dc.identifier.endpage5en_US
dc.identifier.issn2049-9434en_US
dc.identifier.issue6en_US
dc.identifier.pmid33149911en_US
dc.identifier.scopus2-s2.0-85093931893en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.org/10.3892/br.2020.1374
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1168
dc.identifier.volume13en_US
dc.identifier.wosWOS:000595451200008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAkçay, Teoman
dc.language.isoenen_US
dc.publisherSpandidos Publicationsen_US
dc.relation.ispartofBiomedical Reportsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBodybuilderen_US
dc.subjectFitnessen_US
dc.subjectGeneticsen_US
dc.subjectPolymorphismsen_US
dc.subjectSingle Nucleotide Polymorphismen_US
dc.subjectSports Geneticsen_US
dc.titleDistribution of ?-actinin-3 rs1815739 and angiotensin-1 converting enzyme indel polymorphisms in Turkish bodybuildersen_US
dc.typeArticleen_US

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