The effects of diffusion and perfusion MRI mismatch on the admission blood glucose and blood pressure values measured in the first 12 hours of acute stroke

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dc.authoridYakup Krespi / 0000-0001-5246-5908
dc.authorscopusidYakup Krespi / 7005049488
dc.contributor.authorGur-Ozmen, Selen
dc.contributor.authorGungor-Tuncer, Ozlem
dc.contributor.authorKrespi, Yakup
dc.date.accessioned2020-08-30T20:06:46Z
dc.date.available2020-08-30T20:06:46Z
dc.date.issued2019
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractPatients with severe stroke and salvageable brain tissue at admission, who have higher glycaemic and blood pressure levels, may have a risk of iatrogenic hypoglycemia/iatrogenic hypotension. In this study, we examined the relationship between the presence of diffusion-weighted imaging (DWI)/perfusion-weighted imaging (PWI) mismatch, admission blood glucose level, and admission blood pressure level in patients who were admitted in the first 12 hours after onset. We studied 212 patients who were prospectively and consecutively registered to the stroke unit from 2006 to 2009. Correlations between mismatch and admission blood pressure level (ABPL) and admission blood glucose level (ABGL) were analyzed using multivariate logistic regression. Mismatch (P=.064, adjusted OR=2.297, 95% CI, 0.953-5.536) was not associated with a high ABGL in the whole group. However, after excluding patients with diabetes mellitus (DM) (n=67, 35%), mismatch (P=.033, adjusted OR=3.801, 95% CI, 1.110-13.015), an impaired level of consciousness, use of anti-DM medication, glycated hemoglobin levels, and cardioembolic aetiology were independent predictors of a high ABGL. The presence of mismatch or proximal vessel occlusion was not associated with ABPL. Female sex (P=.048) and total anterior circulation stroke (P=.008) were independent predictors associated with a higher ABPL. We conclude that patients with hyperacute ischemic stroke with PWI/DWI mismatch are more likely to have hyperglycemia.en_US
dc.identifier.citationGür-Özmen, S., Güngör–Tunçer, Ö., & Krespi, Y. (2019). The effects of diffusion and perfusion MRI mismatch on the admission blood glucose and blood pressure values measured in the first 12 hours of acute stroke. Medicine, 98(26).en_US
dc.identifier.doi10.1097/MD.0000000000016212en_US
dc.identifier.issn0025-7974en_US
dc.identifier.issn1536-5964en_US
dc.identifier.issue26en_US
dc.identifier.pmid31261574en_US
dc.identifier.scopus2-s2.0-85069269176en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1097/MD.0000000000016212
dc.identifier.urihttps://hdl.handle.net/20.500.12713/615
dc.identifier.volume98en_US
dc.identifier.wosWOS:000480733400084en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKrespi, Yakupen_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofMedicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBlood Glucoseen_US
dc.subjectBlood Pressureen_US
dc.subjectHyperacute Ischemic Strokeen_US
dc.subjectMismatchen_US
dc.subjectPenumbraen_US
dc.titleThe effects of diffusion and perfusion MRI mismatch on the admission blood glucose and blood pressure values measured in the first 12 hours of acute strokeen_US
dc.typeArticleen_US

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