Exploiting urazole’s acidity for fabrication of hydrogels and ion-exchange materials

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dc.authoridAli Zarrabi / 0000-0003-0391-1769en_US
dc.authorscopusidAli Zarrabi / 23483174100en_US
dc.authorwosidAli Zarrabi / U-2602-2019
dc.contributor.authorHanay, Saltuk Bugra
dc.contributor.authorFallah, Ali
dc.contributor.authorSenturk, Efsun
dc.contributor.authorYetim, Zeliha
dc.contributor.authorAfghah, Ferdows
dc.contributor.authorYılmaz, Hülya
dc.contributor.authorCulha, Mustafa
dc.contributor.authorKoc, Bahattin
dc.date.accessioned2021-12-27T13:30:03Z
dc.date.available2021-12-27T13:30:03Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Biyomedikal Mühendisliği Bölümüen_US
dc.description.abstractIn this study, the acidity of urazole (pKa 5–6) was exploited to fabricate a hydrogel in two simple and scalable steps. Commercially available poly(hexamethylene)diisocyanate was used as a precursor to synthesize an urazole containing gel. The formation of urazole was confirmed by FT-IR and1 H-NMR spectroscopy. The hydrogel was characterized by microscopy imaging as well as spectroscopic and thermo-gravimetric analyses. Mechanical analysis and cell viability tests were performed for its initial biocompatibility evaluation. The prepared hydrogel is a highly porous hydrogel with a Young’s modulus of 0.91 MPa, has a swelling ratio of 87%, and is capable of exchanging ions in a medium. Finally, a general strategy was demonstrated to embed urazole groups directly into a crosslinked material.en_US
dc.identifier.citationHanay, S. B., Fallah, A., Senturk, E., Yetim, Z., Afghah, F., Yilmaz, H., ... & Varma, R. S. (2021). Exploiting Urazole’s Acidity for Fabrication of Hydrogels and Ion-Exchange Materials. Gels, 7(4), 261.en_US
dc.identifier.doi10.3390/gels7040261en_US
dc.identifier.issn2310-2861en_US
dc.identifier.issue4en_US
dc.identifier.pmid34940320en_US
dc.identifier.scopus2-s2.0-85121419582en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.3390/gels7040261
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2356
dc.identifier.volume7en_US
dc.identifier.wosWOS:000737620100001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorZarrabi, Ali
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.relation.ispartofGelsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiomaterialsen_US
dc.subjectHydrogelsen_US
dc.subjectIon-Exchangeen_US
dc.subjectPorous Gelsen_US
dc.subjectUrazoleen_US
dc.titleExploiting urazole’s acidity for fabrication of hydrogels and ion-exchange materialsen_US
dc.typeArticleen_US

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