Venous leg symptoms in patients with varicocele: a multicenter assessment study (VEIN-TURKEY study)

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dc.authoridSüleyman Sırrı Kılıç / 0000-0002-0238-8008
dc.authorscopusidSüleyman Sırrı Kılıç / 7006243688
dc.authorwosidSüleyman Sırrı Kılıç / AAO-2348-2020
dc.contributor.authorÖztürk, Selçuk
dc.contributor.authorAkbaba, Kaan Türker
dc.contributor.authorKılıç, Süleyman Sırrı
dc.contributor.authorÇiçek, Tufan
dc.contributor.authorPeşkircioğlu, Levent
dc.contributor.authorTandoğan, İzzet
dc.contributor.authorGürlek, Ahmet
dc.contributor.authorAydemir, Özbay
dc.contributor.authorİleri, Mehmet
dc.contributor.authorYetkin, Ertan
dc.date.accessioned2020-08-30T20:06:57Z
dc.date.available2020-08-30T20:06:57Z
dc.date.issued2019
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionKılıç, Süleyman Sırrı (isu author)
dc.description.abstractObjective The aim of this study is to evaluate chronic venous disease symptoms by using the Venous Insufficiency Epidemiological and Economic Study-Quality of Life/Symptoms (VEINES-QoL/Sym) questionnaire in varicocele patients. Material and methods The study was designed as a prospective, case controlled study and conducted in four hospitals from Turkey. A total of 600 patients who admitted to urology outpatient clinic were enrolled to the study. After the exclusion of 44 patients who do not match the inclusion criteria, the remaining 556 patients were examined for the presence and grade of varicocele and subsequently examined clinically for the presence of chronic venous disease findings. Finally, patients were asked to answer the VEINES-Sym questionnaire consisting of 10 items. All patients' demographic parameters, cardiovascular risk factors, other co-morbid diseases and drug usage were noted. Results Patients were classified into two groups: varicocele (+) group (n=269) and varicocele (-) group (n=287). VEINES-Sym scores of varicocele patients were lower compared to patients without varicocele (41.415.21, 43.19 +/- 3.22, respectively, p<0.001). Grades of varicocele significantly but inversely correlated with VEINES-Sym score (r=0, -206, p=0.001). Logistic regression analysis revealed that presence of varicocele irrespective of grading significantly and independently associated with the presence of aching (odds ratio: 2.054, 95% confidence interval: 1.265-3.338, p=0.004) and throbbing (odds ratio: 2.586, 95% confidence interval: 1.353-4.943, p=0.004). Conclusion Varicocele patients have lower VEINES-Sym scores compared to patients without varicocele and this finding is inversely correlated with the degree of the varicocele. This association supports the hypothesis that there may be a systemic vessel wall abnormality in venous disease patients. Patients with symptoms related to vascular dilatation in any territory may deserve to be assessed systematically with the support of further clinical studies.en_US
dc.description.sponsorshipVascular and Molecular Cardiology Societyen_US
dc.description.sponsorshipThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was funded by Vascular and Molecular Cardiology Society.en_US
dc.identifier.citationOzturk, S., Akbaba, K. T., Kilic, S., Cicek, T., Peskircioglu, L., Tandogan, I., … Yetkin, E. (2019). Venous leg symptoms in patients with varicocele: A multicenter assessment study (VEIN-TURKEY study). PHLEBOLOGY, 34(2), 128–136. https://doi.org/10.1177/0268355518777110en_US
dc.identifier.doi10.1177/0268355518777110en_US
dc.identifier.endpage136en_US
dc.identifier.issn0268-3555en_US
dc.identifier.issn1758-1125en_US
dc.identifier.issue2en_US
dc.identifier.pmid29793400en_US
dc.identifier.scopus2-s2.0-85047410788en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage128en_US
dc.identifier.urihttps://doi.org/10.1177/0268355518777110
dc.identifier.urihttps://hdl.handle.net/20.500.12713/661
dc.identifier.volume34en_US
dc.identifier.wosWOS:000461557800006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKılıç, Süleyman Sırrıen_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofPhlebologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSymptomsen_US
dc.subjectVaricoceleen_US
dc.subjectChronic Venous Diseaseen_US
dc.subjectLeg Diseasesen_US
dc.titleVenous leg symptoms in patients with varicocele: a multicenter assessment study (VEIN-TURKEY study)en_US
dc.typeArticleen_US

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