Generation of induced pluripotent stem cells from patients with multiple myeloma
Yükleniyor...
Dosyalar
Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
gelenos
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Yamanaka and Takahashi made a discovery in the world of life science by transforming mouse somatic fibroblasts into pluripotent cells as a result of transferring 4 gene sets (Sox2-Oct4- Klf4&c-Myc) in 2006 (1). Since that day, induced pluripotent stem cells (iPSCs) are considered to be one of the main sources for regenerative medicine; like embryonic stem cells (ESCs). Because of their pluripotent features, both cell types are building blocks of regenerative medicine. There are no ethical limitations and immunological problems for iPSCs when compared to ESCs (2). Additionally, iPSCs with disease genotypes have been used for human disease modeling (3).
Açıklama
Anahtar Kelimeler
IPS, Multiple Myeloma, MSC, Bone Marrow Mesenchymal Stem Cells, Sendai Virus
Kaynak
Turk J Haematol.
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
Sayı
Künye
Yılmaz Başaran, İ., & Karaöz, E. (2021). Generation of Induced Pluripotent Stem Cells from Patients with Multiple Myeloma. Turkish journal of haematology : official journal of Turkish Society of Haematology, 10.4274/tjh.galenos.2021.2020.0682. Advance online publication. https://doi.org/10.4274/tjh.galenos.2021.2020.0682
