Identification of microenvironmental regulation and therapeutic targeting of oncogenic eEF2K in pancreatic cancer
Yükleniyor...
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Eukaryotic elongation factor 2 kinase (eEF2K) is overexpressed in cancer cells and its overexpression is correlated with poor prognosis in several types of cancer. It has been known that pancreatic cancer (PaCa) has a unique tumor microenvironment (TME) which contributes all stages of tumorigenesis. In this study, the effects of interaction between PaCa cells and macrophages on eEF2K levels and aggressive tumor behaviours were investigated.
Açıklama
Anahtar Kelimeler
Kaynak
Febs Open Bio
WoS Q Değeri
Q3
Scopus Q Değeri
Cilt
9
Sayı
Künye
Zeybek, D. K., Kahraman, N., Bayraktar, R., Kabil, N., Ulukaya, E., Dere, E., & Ozpolat, B. (2019). Identification of microenvironmental regulation and therapeutic targeting of oncogenic eEF2K in pancreatic cancer.
