Identification of microenvironmental regulation and therapeutic targeting of oncogenic eEF2K in pancreatic cancer

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dc.authoridDidem Karakaş Zeybek / 0000-0002-3781-6834en_US
dc.authoridEngin Ulukaya / 0000-0003-4875-5472en_US
dc.authorscopusidDidem Karakaş Zeybek / 56422040600
dc.authorscopusidEngin Ulukaya / 6602927353
dc.authorwosidDidem Karakaş Zeybek / L-6682-2018
dc.authorwosidEngin Ulukaya / K-5792-2018
dc.contributor.authorKarakaş Zeybek, Didem
dc.contributor.authorKahraman, Nermin
dc.contributor.authorBayraktar, Recep
dc.contributor.authorKabil, Nashwa
dc.contributor.authorUlukaya, Engin
dc.contributor.authorDere, Egemen
dc.contributor.authorBerestein, Gabriel Lopez
dc.contributor.authorÖzpolat, Bülent
dc.date.accessioned2020-08-30T20:06:42Z
dc.date.available2020-08-30T20:06:42Z
dc.date.issued2019
dc.departmentİstinye Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji ve Genetik Bölümüen_US
dc.description.abstractEukaryotic elongation factor 2 kinase (eEF2K) is overexpressed in cancer cells and its overexpression is correlated with poor prognosis in several types of cancer. It has been known that pancreatic cancer (PaCa) has a unique tumor microenvironment (TME) which contributes all stages of tumorigenesis. In this study, the effects of interaction between PaCa cells and macrophages on eEF2K levels and aggressive tumor behaviours were investigated.en_US
dc.identifier.citationZeybek, D. K., Kahraman, N., Bayraktar, R., Kabil, N., Ulukaya, E., Dere, E., & Ozpolat, B. (2019). Identification of microenvironmental regulation and therapeutic targeting of oncogenic eEF2K in pancreatic cancer.en_US
dc.identifier.endpage325en_US
dc.identifier.issn2211-5463en_US
dc.identifier.startpage325en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12713/600
dc.identifier.volume9en_US
dc.identifier.wosWOS:000486972405030en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorKarakaş Zeybek, Didemen_US
dc.institutionauthorUlukaya, Enginen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofFebs Open Bioen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleIdentification of microenvironmental regulation and therapeutic targeting of oncogenic eEF2K in pancreatic canceren_US
dc.typeConference Objecten_US

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