Assessment of the relationship between preprocedural C-reactive protein/albumin ratio and stent restenosis in patients with ST-segment elevation myocardial infarction
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Espana Slu
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Introduction: Rent restenosis remains a clinical challenge for patients with ischemic heart disease, since it is associated with repeated coronary interventions as well as higher hospitalization rates and medical costs. Inflammation plays a significant role. Although an association between stent restenosis, increased C-reactive protein (CRP) and decreased albumin levels has been previously reported, no studies have investigated the ability of the CRP/albumin ratio to predict stent restenosis. Methods: This retrospective study included 448 patients who had previously undergone primary percutaneous coronary intervention and who were referred for subsequent reintervention due to recurrence of anginal symptoms. The study population was divided into two groups based on whether the patient had developed stent restenosis. They were then stratified into three groups according to their CRP/albumin ratio. Results: Out of 448 patients, stent restenosis was observed in 24.5% (n=110), as determined by coronary angiography. Patients with stent restenosis had a higher CRP/albumin ratio, greater platelet distribution width (POW), higher CRP levels, and lower levels of both high-density lipoprotein (HDL) cholesterol and serum albumin. The CRP/albumin ratio (OR: 2.289, 95% CI: 1.056-4.959; p=0.036), stent diameter, PDW and HDL cholesterol levels were found to be independent predictors of stent restenosis. A ROC curve comparison demonstrated that the CRP/albumin ratio was a better predictor of restenosis than either albumin and CRP individually, but it was not better than POW and HDL cholesterol. Conclusion: As a novel inflammation-based risk score, the CRP/albumin ratio may be an easily accessible marker for assessment of stent restenosis risk. (C) 2019 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L.U. AU rights reserved.
Açıklama
Anahtar Kelimeler
Stent Restenosis, C-Reactive Protein/Albumin Ratio, St-Segment Elevation Myocardial Infarction, Inflammation
Kaynak
Revista Portuguesa De Cardiologia
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
38
Sayı
4
Künye
Rencuzogullari, I., Karabag, Y., Cagdas, M., Karakoyun, S., Seyis, S., Gursoy, M. O., … Tanboga, I. H. (2019). Assessment of the relationship between preprocedural C-reactive protein/albumin ratio and stent restenosis in patients with ST-segment elevation myocardial infarction. REVISTA PORTUGUESA DE CARDIOLOGIA, 38(4), 269–277. https://doi.org/10.1016/j.repc.2018.08.008
