Assessment of the relationship between preprocedural C-reactive protein/albumin ratio and stent restenosis in patients with ST-segment elevation myocardial infarction

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dc.authoridSabri Seyis / 0000-0002-7980-0363en_US
dc.authorscopusidSabri Seyis / 16176780400
dc.authorwosidSabri Seyis / F-7029-2014
dc.contributor.authorRencuzogullari, Ibrahim
dc.contributor.authorKarabag, Yavuz
dc.contributor.authorCagdas, Metin
dc.contributor.authorKarakoyun, Suleyman
dc.contributor.authorSeyis, Sabri
dc.contributor.authorGursoy, Mustafa Ozan
dc.contributor.authorYesin, Mahmut
dc.contributor.authorArtac, Inanc
dc.contributor.authorIlis, Dogan
dc.contributor.authorTanboga, Ibrahim Halil
dc.date.accessioned2020-08-30T20:06:51Z
dc.date.available2020-08-30T20:06:51Z
dc.date.issued2019
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractIntroduction: Rent restenosis remains a clinical challenge for patients with ischemic heart disease, since it is associated with repeated coronary interventions as well as higher hospitalization rates and medical costs. Inflammation plays a significant role. Although an association between stent restenosis, increased C-reactive protein (CRP) and decreased albumin levels has been previously reported, no studies have investigated the ability of the CRP/albumin ratio to predict stent restenosis. Methods: This retrospective study included 448 patients who had previously undergone primary percutaneous coronary intervention and who were referred for subsequent reintervention due to recurrence of anginal symptoms. The study population was divided into two groups based on whether the patient had developed stent restenosis. They were then stratified into three groups according to their CRP/albumin ratio. Results: Out of 448 patients, stent restenosis was observed in 24.5% (n=110), as determined by coronary angiography. Patients with stent restenosis had a higher CRP/albumin ratio, greater platelet distribution width (POW), higher CRP levels, and lower levels of both high-density lipoprotein (HDL) cholesterol and serum albumin. The CRP/albumin ratio (OR: 2.289, 95% CI: 1.056-4.959; p=0.036), stent diameter, PDW and HDL cholesterol levels were found to be independent predictors of stent restenosis. A ROC curve comparison demonstrated that the CRP/albumin ratio was a better predictor of restenosis than either albumin and CRP individually, but it was not better than POW and HDL cholesterol. Conclusion: As a novel inflammation-based risk score, the CRP/albumin ratio may be an easily accessible marker for assessment of stent restenosis risk. (C) 2019 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L.U. AU rights reserved.en_US
dc.identifier.citationRencuzogullari, I., Karabag, Y., Cagdas, M., Karakoyun, S., Seyis, S., Gursoy, M. O., … Tanboga, I. H. (2019). Assessment of the relationship between preprocedural C-reactive protein/albumin ratio and stent restenosis in patients with ST-segment elevation myocardial infarction. REVISTA PORTUGUESA DE CARDIOLOGIA, 38(4), 269–277. https://doi.org/10.1016/j.repc.2018.08.008en_US
dc.identifier.doi10.1016/j.repc.2018.08.008en_US
dc.identifier.endpage277en_US
dc.identifier.issn0870-2551en_US
dc.identifier.issn0304-4750en_US
dc.identifier.issue4en_US
dc.identifier.pmid31104927en_US
dc.identifier.scopus2-s2.0-85065623600en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage269en_US
dc.identifier.urihttps://doi.org/10.1016/j.repc.2018.08.008
dc.identifier.urihttps://hdl.handle.net/20.500.12713/638
dc.identifier.volume38en_US
dc.identifier.wosWOS:000471271900007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSeyis, Sabrien_US
dc.language.isoenen_US
dc.publisherElsevier Espana Sluen_US
dc.relation.ispartofRevista Portuguesa De Cardiologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectStent Restenosisen_US
dc.subjectC-Reactive Protein/Albumin Ratioen_US
dc.subjectSt-Segment Elevation Myocardial Infarctionen_US
dc.subjectInflammationen_US
dc.titleAssessment of the relationship between preprocedural C-reactive protein/albumin ratio and stent restenosis in patients with ST-segment elevation myocardial infarctionen_US
dc.typeArticleen_US

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