The effect of laparoscopic sleeve gastrectomy on nonalcoholic fatty liver disease
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams & Wilkins
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Obesity is associated with nonalcoholic fatty liver disease which is one of the most common causes of chronic liver disease. FibroScan is a noninvasive tool for liver stiffness measurement and controlled attenuation parameter to evaluate liver steatosis and fibrosis. We aimed to demonstrate the effect of laparoscopic sleeve gastrectomy on liver steatosis and fibrosis. Of the 120 consecutive patients screened, 72 were enrolled in this study. FibroScan M probe and XL probe were used for the evaluation of liver steatosis and fibrosis. Fifty-two patients (72.2%) were female individuals and 20 (27.8%) were male individuals; the mean age was 37.9 +/- 10.4 years. Percentage of excess weight loss was significant at the third and sixth months: 57.2 +/- 18.3 (P<0.05) and 81.4 +/- 24.6 (P<0.05), respectively. Mean preoperative controlled attenuation parameter and liver stiffness measurement values were 309.2 +/- 68.7 dB/m and 7.5 +/- 5.0 kPa, respectively, and significantly declined to 217.4 +/- 56.4 dB/m and 5.6 +/- 2.5 kPa, respectively, at sixth postoperative month (P<0.001 and <0.01, respectively). These results suggest that laparoscopic sleeve gastrectomy is associated with significant improvement in liver steatosis and fibrosis. Bariatric surgery has a beneficial effect on nonalcoholic fatty liver disease in morbidly obese patients.
Açıklama
PubMed: 31107849
Anahtar Kelimeler
Sleeve Gastrectomy, Transient Elastography, Nonalcoholic Fatty Liver Disease, Bariatric Surgery
Kaynak
Surgical Laparoscopy Endoscopy & Percutaneous Techniques
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
29
Sayı
6
Künye
Batman, B., Altun, H., Simsek, B., Aslan, E., & Namli Koc, S. (2019). The effect of laparoscopic sleeve gastrectomy on nonalcoholic fatty liver disease. Surgical laparoscopy, endoscopy & percutaneous techniques, 29(6), 509-512.
