Gastroesophageal reflux disease and the relationship with Helicobacter pylori
Yükleniyor...
Dosyalar
Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Aves
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
After Helicobacter pylori was identified, and its relationship with peptic ulcer disease was exactly shown, the relationship of this bacterium with gastroesophageal reflux disease (GERD) gained momentum and discussions continue to this day. We reviewed the literature for the relationship between H. pylori and GERD. According to the existing data, there is no relationship between GERD and H. pylori presence. Successful eradication therapy does not have an impact on the emergence or exacerbation of GERD. However Barrett's esophagus and esophageal adenocarcinoma are less frequent, especially in the presence of CagA positive H. pylori infections. Longterm use of proton pump inhibitor (PPI) may have an impact on the development of atrophy and/or intestinal metaplasia in H. pylori positive patients; therefore, H. pylori eradication is recommended in patients that should use long-term PPI. As a conclusion, H. pylori screening and the eradication decision should be independent of GERD, except for patients that will use long-term PPI.
Açıklama
Anahtar Kelimeler
Helicobacter Pylori, Gastroesophageal Reflux Disease, Proton Pump Inhibitors, Gastric Atrophy, Esophagus Cancer, Barrett Esophagus
Kaynak
Turkish Journal of Gastroenterology
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
28
Sayı
Künye
Mungan, Z., & Şimşek, B. P. (2017). Gastroesophageal reflux disease and the relationship with helicobacter pylori. Turkish Journal of Gastroenterology, 28, S61–S67. https://doi.org/10.5152/tjg.2017.16
