Next-Generation Hydrogels as Biomaterials for Biomedical Applications: Exploring the Role of Curcumin
Küçük Resim Yok
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Amer Chemical Soc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Since the first report on the pharmacological activity of curcumin in 1949, enormous amounts of research have reported diverse activities for this natural polyphenol found in the dietary spice turmeric. However, curcumin has not yet been used for human application as an approved drug. The clinical translation of curcumin has been hampered due to its low solubility and bioavailability. The improvement in bioavailability and solubility of curcumin can be achieved by its formulation using drug delivery systems. Hydrogels with their biocompatibility and low toxicity effects have shown a substantial impact on the successful formulation of hydrophobic drugs for human clinical trials. This review focuses on hydrogel-based delivery systems for curcumin and describes its applications as anti-cancer as well as wound healing agents.
Açıklama
Anahtar Kelimeler
Improving Antitumor-Activity, Effectively Kill Bacteria, Cellulose-Based Hydrogels, Drug-Delivery Systems, Situ-Forming Hydrogel, In-Vitro, Beta-Cyclodextrin, Sustained-Release, Loaded Hydrogel, Conjugated Polyethylenimine
Kaynak
Acs Omega
WoS Q Değeri
N/A
Scopus Q Değeri
Q1
Cilt
8
Sayı
10
