Next-Generation Hydrogels as Biomaterials for Biomedical Applications: Exploring the Role of Curcumin

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dc.authoridThakur, Vijay Kumar/0000-0002-0790-2264
dc.authoridDehshahri, Ali/0000-0003-4458-1292
dc.authorwosidThakur, Vijay Kumar/J-1691-2015
dc.contributor.authorMadamsetty, Vijay Sagar
dc.contributor.authorVazifehdoost, Maryam
dc.contributor.authorAlhashemi, Samira Hossaini
dc.contributor.authorDavoudi, Hesam
dc.contributor.authorZarrabi, Ali
dc.contributor.authorDehshahri, Ali
dc.contributor.authorFekri, Hojjat Samareh
dc.date.accessioned2024-05-19T14:50:34Z
dc.date.available2024-05-19T14:50:34Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractSince the first report on the pharmacological activity of curcumin in 1949, enormous amounts of research have reported diverse activities for this natural polyphenol found in the dietary spice turmeric. However, curcumin has not yet been used for human application as an approved drug. The clinical translation of curcumin has been hampered due to its low solubility and bioavailability. The improvement in bioavailability and solubility of curcumin can be achieved by its formulation using drug delivery systems. Hydrogels with their biocompatibility and low toxicity effects have shown a substantial impact on the successful formulation of hydrophobic drugs for human clinical trials. This review focuses on hydrogel-based delivery systems for curcumin and describes its applications as anti-cancer as well as wound healing agents.en_US
dc.identifier.doi10.1021/acsomega.2c07062
dc.identifier.endpage8976en_US
dc.identifier.issn2470-1343
dc.identifier.issue10en_US
dc.identifier.pmid36936324en_US
dc.identifier.scopus2-s2.0-85149139760en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage8960en_US
dc.identifier.urihttps://doi.org10.1021/acsomega.2c07062
dc.identifier.urihttps://hdl.handle.net/20.500.12713/5747
dc.identifier.volume8en_US
dc.identifier.wosWOS:000941510300001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAmer Chemical Socen_US
dc.relation.ispartofAcs Omegaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectImproving Antitumor-Activityen_US
dc.subjectEffectively Kill Bacteriaen_US
dc.subjectCellulose-Based Hydrogelsen_US
dc.subjectDrug-Delivery Systemsen_US
dc.subjectSitu-Forming Hydrogelen_US
dc.subjectIn-Vitroen_US
dc.subjectBeta-Cyclodextrinen_US
dc.subjectSustained-Releaseen_US
dc.subjectLoaded Hydrogelen_US
dc.subjectConjugated Polyethylenimineen_US
dc.titleNext-Generation Hydrogels as Biomaterials for Biomedical Applications: Exploring the Role of Curcuminen_US
dc.typeReview Articleen_US

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