Analysis of denver neurodevelopmental screening test results of myelomeningocele, hydrocephalus, and microcephaly patients
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Dosyalar
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Medknow Publications & Media Pvt Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Context: Spina bifida, hydrocephalus, and similar congenital central nervous system (CNS) anomalies take origin from embryologic stages weeks before birth, but assessment and follow-up of these patients are important to figure and predict the effects of these anomalies on child's neurodevelopment. Aims: To evaluate of multiple groups of congenital CNS anomalies in the neurodevelopment level. Settings and Design: The study was conducted at a research and treatment center for spina bifida patients. Materials and Methods: The study group included 348 patients with a mean age of 15.4 (+/- 15.1) months, who had spina bifida aperta, hydrocephalus, and microcephaly. Patients with other known intracranial conditions were excluded. The subjects were evaluated into five groups: Group 1, 88 patients with congenital hydrocephalus; Group 2, 48 patients with congenital hydrocephalus and ventriculoperitoneal shunt; Group 3, 148 patients with microcephaly; Group 4, 30 patients who were operated for spina bifida aperta; and Group 5, 39 patients who were operated for spina bifida aperta and also had ventriculoperitoneal shunt implantation. Denver Developmental Screening Test II was used to assess patients' neurodevelopment levels. Statistical Analysis Used: Pearson's chi-square and Fisher's exact tests were used for data analysis. Group comparisons were also made in pairs with chi-square test according to Bonferroni corrections. Frequency of abnormal findings was significantly correlated with age (P = 0.014). Results: Total score differences of five groups appeared to be statistically significant according to Pearson's chi-square test (P = 0.000). When we compared groups in pairs, abnormal results were significantly frequent in shunted groups (P < 0.01). Conclusions: Our results suggested that shunt-dependent hydrocephalus caused serious neurodevelopmental impairments in patients.
Açıklama
Anahtar Kelimeler
Denver Neurodevelopmental Screening Test, Hydrocephalus, Microcephaly, Neurodevelopment, Spina Bifida, Ventriculoperitoneal Shunt
Kaynak
Journal of Pediatric Neurosciences
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
13
Sayı
1
Künye
Alatas, I., Canaz, G., Arslan, G., Cevik, S., Kacmaz, B., Kara, N., & Canaz, H. (2018). Analysis of Denver Neurodevelopmental Screening Test results of myelomeningocele, hydrocephalus, and microcephaly patients. Journal of pediatric neurosciences, 13(1), 28.
