Analysis of denver neurodevelopmental screening test results of myelomeningocele, hydrocephalus, and microcephaly patients

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dc.authoridSerdar Çevik / 0000-0002-2733-4233
dc.authorscopusidSerdar Çevik / 56516611400
dc.authorwosidSerdar Çevik / G-7161-2018
dc.contributor.authorAlataş, İbrahim
dc.contributor.authorCanaz, Gökhan
dc.contributor.authorArslan, Gülseren
dc.contributor.authorÇevik, Serdar
dc.contributor.authorKaçmaz, Belgü
dc.contributor.authorKara, Nursu
dc.contributor.authorCanaz, Huseyin
dc.date.accessioned2020-08-30T20:07:52Z
dc.date.available2020-08-30T20:07:52Z
dc.date.issued2018
dc.departmentİstinye Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Anestezi Bölümüen_US
dc.description.abstractContext: Spina bifida, hydrocephalus, and similar congenital central nervous system (CNS) anomalies take origin from embryologic stages weeks before birth, but assessment and follow-up of these patients are important to figure and predict the effects of these anomalies on child's neurodevelopment. Aims: To evaluate of multiple groups of congenital CNS anomalies in the neurodevelopment level. Settings and Design: The study was conducted at a research and treatment center for spina bifida patients. Materials and Methods: The study group included 348 patients with a mean age of 15.4 (+/- 15.1) months, who had spina bifida aperta, hydrocephalus, and microcephaly. Patients with other known intracranial conditions were excluded. The subjects were evaluated into five groups: Group 1, 88 patients with congenital hydrocephalus; Group 2, 48 patients with congenital hydrocephalus and ventriculoperitoneal shunt; Group 3, 148 patients with microcephaly; Group 4, 30 patients who were operated for spina bifida aperta; and Group 5, 39 patients who were operated for spina bifida aperta and also had ventriculoperitoneal shunt implantation. Denver Developmental Screening Test II was used to assess patients' neurodevelopment levels. Statistical Analysis Used: Pearson's chi-square and Fisher's exact tests were used for data analysis. Group comparisons were also made in pairs with chi-square test according to Bonferroni corrections. Frequency of abnormal findings was significantly correlated with age (P = 0.014). Results: Total score differences of five groups appeared to be statistically significant according to Pearson's chi-square test (P = 0.000). When we compared groups in pairs, abnormal results were significantly frequent in shunted groups (P < 0.01). Conclusions: Our results suggested that shunt-dependent hydrocephalus caused serious neurodevelopmental impairments in patients.en_US
dc.identifier.citationAlatas, I., Canaz, G., Arslan, G., Cevik, S., Kacmaz, B., Kara, N., & Canaz, H. (2018). Analysis of Denver Neurodevelopmental Screening Test results of myelomeningocele, hydrocephalus, and microcephaly patients. Journal of pediatric neurosciences, 13(1), 28.en_US
dc.identifier.doi10.4103/jpn.JPN_156_17en_US
dc.identifier.endpage33en_US
dc.identifier.issn1817-1745en_US
dc.identifier.issn1998-3948en_US
dc.identifier.issue1en_US
dc.identifier.pmid29899768en_US
dc.identifier.scopus2-s2.0-85047240715en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage28en_US
dc.identifier.urihttps://doi.org/10.4103/jpn.JPN_156_17
dc.identifier.urihttps://hdl.handle.net/20.500.12713/846
dc.identifier.volume13en_US
dc.identifier.wosWOS:000433244300005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÇevik, Serdaren_US
dc.language.isoenen_US
dc.publisherMedknow Publications & Media Pvt Ltden_US
dc.relation.ispartofJournal of Pediatric Neurosciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDenver Neurodevelopmental Screening Testen_US
dc.subjectHydrocephalusen_US
dc.subjectMicrocephalyen_US
dc.subjectNeurodevelopmenten_US
dc.subjectSpina Bifidaen_US
dc.subjectVentriculoperitoneal Shunten_US
dc.titleAnalysis of denver neurodevelopmental screening test results of myelomeningocele, hydrocephalus, and microcephaly patientsen_US
dc.typeArticleen_US

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