Role of serum levels of tumour necrosis factor-like weak inducer of apoptosis (TWEAK) in predicting severity of acute appendicitis

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dc.authoridISMAN, FERRUH/0000-0003-4278-4651
dc.authoridAkın, Merve/0000-0001-7224-4774
dc.authoridYASTI, AHMET CINAR/0000-0002-1281-3549
dc.authoridZulfikaroglu, Baris/0000-0003-4782-0308
dc.authoridozmen, mehmet mahir/0000-0003-0649-0111
dc.authorwosidIsman, ferruh/JVO-8127-2024
dc.authorwosidISMAN, FERRUH/JVO-4679-2024
dc.authorwosidAkın, Merve/AAV-6282-2020
dc.contributor.authorZulfikaroglu, Baris
dc.contributor.authorAkkurt, Gokhan
dc.contributor.authorAkin, Merve
dc.contributor.authorIsman, Ferruh Kemal
dc.contributor.authorYasti, Ahmet Cinar
dc.contributor.authorOzmen, Mehmet Mahir
dc.date.accessioned2024-05-19T14:38:49Z
dc.date.available2024-05-19T14:38:49Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractObjective: One of the most prevalent abdominal crises is acute appendicitis (AA). Clinical diagnosis, even for skilled surgeons, is frequently challenging, as indicated by the high proportion of negative investigations. The purpose of this study was to see if serum TWEAK levels might be used to diagnose acute appendicitis. Material and Methods: Between June 2017 and May 2019, all patients who had surgery with the original diagnosis of AA were included in the study. TWEAK, WBC, CRP, and bilirubin levels were compared. Results: The levels of WBC, CRP, and bilirubin were compared to pathology. All three blood indicators increased significantly in AA patients. However, no statistically significant difference in the levels of all three blood indicators was seen between individuals with simple AA and those with severe AA. TWEAK plasma concentrations were considerably greater in patients with severe AA than in the healthy control and NAA groups. TWEAK levels were significantly greater in individuals with severe AA compared to patients with simple AA. Conclusion: Serum TWEAK levels that are elevated may be used to diagnose acute appendicitis as well as prognostic indicators for the severity of appendicitis.en_US
dc.identifier.doi10.47717/turkjsurg.2023.5747
dc.identifier.endpage127en_US
dc.identifier.issn2564-6850
dc.identifier.issn2564-7032
dc.identifier.issue2en_US
dc.identifier.pmid38026909en_US
dc.identifier.scopus2-s2.0-85165091689en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage121en_US
dc.identifier.trdizinid1185174en_US
dc.identifier.urihttps://doi.org10.47717/turkjsurg.2023.5747
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1185174
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4617
dc.identifier.volume39en_US
dc.identifier.wosWOS:001065278300007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTurkish Surgical Assocen_US
dc.relation.ispartofTurkish Journal of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectAcute Appendicitisen_US
dc.subjectInflammationen_US
dc.subjectMarkeren_US
dc.subjectSeverityen_US
dc.subjectTumor Necrosis Factor-Like Weak Inducer Of Apoptosisen_US
dc.titleRole of serum levels of tumour necrosis factor-like weak inducer of apoptosis (TWEAK) in predicting severity of acute appendicitisen_US
dc.typeArticleen_US

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