Early experience with salvage robotic-assisted radical prostatectomy in proton beam radiotherapy failures

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dc.authoridYaşar Bozkurt / 0000-0003-3916-6625en_US
dc.authorscopusidYaşar Bozkurt / 36185179700
dc.authorwosidYaşar Bozkurt / CFN-9160-2022
dc.contributor.authorBozkurt, Yaşar
dc.contributor.authorAtar, Murat
dc.contributor.authorPisters, Louis L.
dc.date.accessioned2021-09-09T10:03:21Z
dc.date.available2021-09-09T10:03:21Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractAims: To assess the perioperative and short-term functional and oncologic outcomes of the salvage robot-assisted radical prostatectomy (sRARP), after recurrence following primary proton beam therapy for clinically localized prostate cancer. Methods: Ten patients undergoing sRARP after failure of the prior definitive proton beam therapy for localized prostate cancer were included. BCR is defined as a prostate-specific antigen (PSA) value of 2.0 ng/mL greater than the absolute nadir. All of the individuals had a diagnosis of prostate cancer via biopsy after proton beam therapy, with negative findings on magnetic resonance imaging/computer tomography of the pelvis and abdomen, and a bone scan. The sRARP procedure with pelvic lymph node dissection was performed by a single surgeon in all patients. Results: The median age of the cohort at sRARP was 66.8 years, and the mean BMI was 29.2 kg/m2. The mean duration from proton beam therapy to sRARP was 58.4 months; the mean preoperative PSA level was 5.5 ng/mL, the mean operative time was 230 minutes, and the approximate blood loss was 745 mL. Anastomotic leakage occurred in half of the individuals, and bladder neck contracture developed in 6 patients. For 8 patients, the continence results within 6 months followup were available. Overall, 24 complications occurred in 9 patients. At follow-up in the 32nd month, the overall survival rate was 80%, and the BCR-free survival rate was 90%. Conclusion: sRARP after proton beam therapy is an applicable procedure, but has a high risk of serious complications.en_US
dc.identifier.citationBozkurt, Y., Atar, M., & Pisters, L. L. (2021). Early Experience with Salvage Robotic-Assisted Radical Prostatectomy in Proton Beam Radiotherapy Failures. Balkan medical journal, 10.5152/balkanmedj.2021.21174. Advance online publication. https://doi.org/10.5152/balkanmedj.2021.21174en_US
dc.identifier.doi10.5152/balkanmedj.2021.21174en_US
dc.identifier.endpage315en_US
dc.identifier.issue5en_US
dc.identifier.pmid34462255en_US
dc.identifier.scopus2-s2.0-85115354403en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage310en_US
dc.identifier.trdizinid481661en_US
dc.identifier.urihttps://doi.org/10.5152/balkanmedj.2021.21174
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2033
dc.identifier.volume38en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBozkurt, Yaşar
dc.language.isoenen_US
dc.publisherGalenosen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEarly experience with salvage robotic-assisted radical prostatectomy in proton beam radiotherapy failuresen_US
dc.typeArticleen_US

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