Role of bacteriological agents in idiopathic granulomatous mastitis: real or not ?
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Aves
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: Granulomatous mastitis is a rare, benign, chronic inflammatory disease of the breast of unknown etiology. This study evaluated bacteriologic agents that might play a role in the etiology of granulomatous mastitis using a molecular method with a universal primer after isolating deoxyribonucleic acid (DNA) from pathology specimens from patients diagnosed with granulomatous mastitis. Materials and Methods: Breast biopsy material in the pathology department obtained between July 2008 and June 2013 was analyzed. The history of the granulomatous mastitis patients was examined in detail and paraffin block sections of the biopsy material were used to determine the presence of bacteria with a universal DNA primer. Results: This study examined 45 granulomatous mastitis patients who had been diagnosed using excisional, incisional, or core biopsies. We evaluated multiple bacterial taxa, but obtained no positive result using a nucleic-acid-based assay with a universal primer. Conclusion: The etiology of idiopathic granulomatous mastitis remains unclear. Further studies with a large number of patients should aim to identify the causative agent.
Açıklama
Anahtar Kelimeler
Mastitis, Granulomatous Mastitis, Idiopathic Granulomatous Mastitis, Bacteria, Etiology
Kaynak
European Journal of Breast Health
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
15
Sayı
1
Künye
Kıvılcım, T., Altıntoprak, F., Memiş, B., Ferhatoğlu, M. F., Kartal, A., Dikicier, E., ... & Dilek, F. H. (2019). Role of bacteriological agents in idiopathic granulomatous mastitis: real or not?. European journal of breast health, 15(1), 32.
