Are the factors affecting adverse pregnancy outcomes different in obese gestational diabetes pregnant women receiving diet or insulin treatment?

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Küçük Resim

Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Editura Acad Romane

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Context. We aimed to examine the factors affecting adverse gestational outcome in gestational diabetes (GDM) patients, who were grouped as obese and normal-weight, having only-diet, or insulin treatments. Subjects and Methods. The study included 373 patients, treated with diet or insulin. These patients were sub-grouped as obese and non-obese, and examined retrospectively. The variables affecting adverse gestational outcome in obese GDM patients having dietary and/or insulin treatments were detected with multiple regression analysis. Results. The weight gained during pregnancy in the GDM group having insulin treatment was more than the one in only-diet treated GDM group (p=0.004). Pre-pregnancy body mass index, the weight gained during pregnancy, hemoglobin A1C levels in the second and third trimesters, caesarian rates were higher in the insulin-treated obese patients than in the other groups (p<0.001). The odds ratio for fasting blood glucose level in insulin-treated obese GDM group was 1.081 (95% CI = 1.004 - 1.163) (p=0.039); and it was 0.982 (95% CI = 0.924 - 1.002) (p=0.048) for the weight gained during pregnancy, in only-diet treated obese GDM patients. Conclusion. The control of weight gained during pregnancy, and of fasting blood glucose levels in obese patients having GDM, is important to decrease adverse gestational outcome.

Açıklama

Anahtar Kelimeler

Obese Gestational Diabetes, Adverse Pregnancy Outcomes, Weight Gain During Pregnancy, Diet Therapy, Insulin Therapy

Kaynak

Acta Endocrinologica-Bucharest

WoS Q Değeri

Q4

Scopus Q Değeri

Q4

Cilt

15

Sayı

4

Künye

Ozler, S., Oztas, E., Guler, B. G., Alci, M., Caglar, A. T., & Danisman, N. (2019). ARE THE FACTORS AFFECTING ADVERSE PREGNANCY OUTCOMES DIFFERENT IN OBESE GESTATIONAL DIABETES PREGNANT WOMEN RECEIVING DIET OR INSULIN TREATMENT? ACTA ENDOCRINOLOGICA-BUCHAREST, 15(4), 472–481. https://doi.org/10.4183/aeb.2019.472