Biomedical applications of engineered heparin-based materials
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Keai Publishing Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Heparin is a negatively charged polysaccharide with various chain lengths and a hydrophilic backbone. Due to its fascinating chemical and physical properties, nontoxicity, biocompatibility, and biodegradability, heparin has been extensively used in different fields of medicine, such as cardiovascular and hematology. This review highlights recent and future advancements in designing materials based on heparin for various biomedical ap-plications. The physicochemical and mechanical properties, biocompatibility, toxicity, and biodegradability of heparin are discussed. In addition, the applications of heparin-based materials in various biomedical fields, such as drug/gene delivery, tissue engineering, cancer therapy, and biosensors, are reviewed. Finally, challenges, opportunities, and future perspectives in preparing heparin-based materials are summarized.
Açıklama
Anahtar Kelimeler
Heparin, Nanomaterials, Physicochemical, Biological, Preparation
Kaynak
Bioactive Materials
WoS Q Değeri
N/A
Scopus Q Değeri
Q1
Cilt
31
