Biomedical applications of engineered heparin-based materials

Basit Öğe Kaydı
dc.authoridOzdemir, Fatma/0000-0002-1109-0588
dc.authoridAgarwal, Tarun/0000-0002-3300-7781
dc.authoridMostafavi, Ebrahim/0000-0003-3958-5002
dc.authoridKhan, Prof. Dr. Haroon/0000-0002-1736-4404
dc.authoridKHORSANDI, DANIAL/0000-0002-5245-5555
dc.authoridYilmaz, Hulya/0000-0003-4592-6432
dc.authoridHooshmand, Sara/0000-0003-2417-8797
dc.authorwosidOzdemir, Fatma/ABC-2686-2020
dc.authorwosidYilmaz, Hulya/AAJ-6537-2020
dc.authorwosidAgarwal, Tarun/AAT-8801-2021
dc.authorwosidMostafavi, Ebrahim/X-3674-2019
dc.authorwosidKhan, Prof. Dr. Haroon/AAY-1785-2020
dc.contributor.authorZare, Ehsan Nazarzadeh
dc.contributor.authorKhorsandi, Danial
dc.contributor.authorZarepour, Atefeh
dc.contributor.authorYilmaz, Hulya
dc.contributor.authorAgarwal, Tarun
dc.contributor.authorHooshmand, Sara
dc.contributor.authorMohammadinejad, Reza
dc.date.accessioned2024-05-19T14:42:20Z
dc.date.available2024-05-19T14:42:20Z
dc.date.issued2024
dc.departmentİstinye Üniversitesien_US
dc.description.abstractHeparin is a negatively charged polysaccharide with various chain lengths and a hydrophilic backbone. Due to its fascinating chemical and physical properties, nontoxicity, biocompatibility, and biodegradability, heparin has been extensively used in different fields of medicine, such as cardiovascular and hematology. This review highlights recent and future advancements in designing materials based on heparin for various biomedical ap-plications. The physicochemical and mechanical properties, biocompatibility, toxicity, and biodegradability of heparin are discussed. In addition, the applications of heparin-based materials in various biomedical fields, such as drug/gene delivery, tissue engineering, cancer therapy, and biosensors, are reviewed. Finally, challenges, opportunities, and future perspectives in preparing heparin-based materials are summarized.en_US
dc.identifier.doi10.1016/j.bioactmat.2023.08.002
dc.identifier.endpage118en_US
dc.identifier.issn2452-199X
dc.identifier.pmid37609108en_US
dc.identifier.scopus2-s2.0-85167444179en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage87en_US
dc.identifier.urihttps://doi.org10.1016/j.bioactmat.2023.08.002
dc.identifier.urihttps://hdl.handle.net/20.500.12713/5230
dc.identifier.volume31en_US
dc.identifier.wosWOS:001053107700001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherKeai Publishing Ltden_US
dc.relation.ispartofBioactive Materialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectHeparinen_US
dc.subjectNanomaterialsen_US
dc.subjectPhysicochemicalen_US
dc.subjectBiologicalen_US
dc.subjectPreparationen_US
dc.titleBiomedical applications of engineered heparin-based materialsen_US
dc.typeReview Articleen_US

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