Total knee arthroplasty postsurgical chronic pain, neuropathic pain, and the prevalence of neuropathic symptoms: a prospective observational study in Turkey

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dc.authoridSerbülent Gökhan Beyaz / 0000-0001-9263-7823
dc.authorscopusidSerbülent Gökhan Beyaz / 36623282200
dc.authorwosidSerbülent Gökhan Beyaz / D-7095-2011
dc.contributor.authorSahin, Fatih
dc.contributor.authorBeyaz, Serbülent Gökhan
dc.contributor.authorKarakus, Nazim
dc.contributor.authorInanmaz, Mustafa Erkan
dc.date.accessioned2021-05-31T08:20:42Z
dc.date.available2021-05-31T08:20:42Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose: Chronic post-surgical pain (CPSP) is a detrimental condition that persists at least two months after surgical procedures and seriously affects patients' quality of life. Although its incidence varies according to operation types and definitions, its prevalence is between 3% and 85%. The purpose of this study is to evaluate the prevalence of CPSP and neuropathic pain in patients undergoing TKA for osteoarthritis. Patients and Methods: In this study, patients who had undergone total knee arthroplasty (TKA) were examined prospectively and observationally. 42 patients were included in the study. Numeric rate scale (NRS) for developing chronic pain, Douleur Neuropathique 4 (DN-4) questionnaire to evaluate neuropathic pain and symptoms, and von Frey filaments to evaluate mechanical hyperesthesia and alladony. Results: NRS scores were 1 or higher for all patients. Twenty-seven patients constituted the mild pain group (NRS: 1-4), and 15 patients constituted the moderate pain group (NRS: 4-7). The number of patients defined as having "neuropathic pain," according to DN-4 scores, was 17 (40.4%; DN-4 >= 4). The moderate pain group reported greater severity of neuropathic symptoms on average than the mild pain group (p = 0.039). When patients knees affected by TKA were divided into suprapatellar, patellar, and infrapatellar regions and evaluated with von Frey filaments, a significant difference was found between the three regions (p < 0.05). Conclusion: In this study, we showed-unlike other studies-that the rate of neuropathic pain was higher among CPSP patients, and all patients had neuropathic symptoms. In evaluating patients knees with von Frey filaments, we showed that the neuropathic component of patients' pain occurred mostly in the knee's infrapatellar region. Although the incidence of CPSP and neuropathic pain in these patients was higher than expected, we think CPSP, its diagnosis, and its treatment present an important issue that requires further examination.en_US
dc.identifier.citationŞahin, F., Beyaz, S. G., Karakuş, N., & İnanmaz, M. E. (2021). Total Knee Arthroplasty Postsurgical Chronic Pain, Neuropathic Pain, and the Prevalence of Neuropathic Symptoms: A Prospective Observational Study in Turkey. Journal of Pain Research, 14, 1315.en_US
dc.identifier.doi10.2147/JPR.S293856en_US
dc.identifier.endpage1321en_US
dc.identifier.issn1178-7090en_US
dc.identifier.pmid34040434en_US
dc.identifier.scopus2-s2.0-85107452658en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1315en_US
dc.identifier.urihttps://www.doi.org/10.2147/JPR.S293856
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1771
dc.identifier.volume14en_US
dc.identifier.wosWOS:000653037900001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBeyaz, Serbülent Gökhan
dc.language.isoenen_US
dc.publisherDOVE MEDICAL PRESS LTDen_US
dc.relation.ispartofJOURNAL OF PAIN RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChronic Postsurgical Painen_US
dc.subjectNeuropathic Painen_US
dc.subjectNeuropathic Symptomen_US
dc.subjectVon Frey Filamenten_US
dc.subjectTotal Knee Arthroplastyen_US
dc.titleTotal knee arthroplasty postsurgical chronic pain, neuropathic pain, and the prevalence of neuropathic symptoms: a prospective observational study in Turkeyen_US
dc.typeArticleen_US

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