Assessment of sleep pattern and quality before and after liver transplantation using different methods

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dc.authoridAyhan Dinçkan / 0000-0003-1395-333Xen_US
dc.authorscopusidAyhan Dinçkan / 8656794300
dc.authorwosidAyhan Dinçkan / AAO-2633-2020
dc.contributor.authorGençdal, Genco
dc.contributor.authorTürker, Gamze
dc.contributor.authorGençdal, Işıl Yazıcı
dc.contributor.authorEkinci, Burçak
dc.contributor.authorAcar, Sencan
dc.contributor.authorDinçkan, Ayhan
dc.contributor.authorAkyıldız, Murat
dc.date.accessioned2020-10-07T08:01:02Z
dc.date.available2020-10-07T08:01:02Z
dc.date.issued2020
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground/Aims: Sleep disorders (SDs) are frequently seen in patients with liver cirrhosis. Polysomnography (PSG), actigraphy, and electroencephalogram (EEG) are the common objective methods to diagnose SDs. The most commonly used subjective methods are the Pittsburgh sleep quality index (PSQI) and Epworth sleepiness scale (ESS). We aimed to evaluate the effect of liver transplantation (LTx) on SDs using a combination of objective (PSG and EEG) and subjective (PSQI and ESS) methods. Materials and Methods: A total of 18 patients with cirrhosis on an LTx waiting list were included in this study. Patient clinical status and biochemical parameters were evaluated. All patients completed the validated Turkish forms of the PSQI and ESS before and 9 months after LTx. All patients underwent EEG and PSG before and 9 months after LTx. Results: In total, 18 patients with liver cirrhosis (men: 12; 66.7%, mean age: 53.22 +/- 10.43 years) were included in this study. Pretransplant mean PSQI and ESS scores were 8.4 +/- 3.11 and 7.28 +/- 3.89, respectively; 9-month posttransplant mean PSQI and ESS scores were 4.5 +/- 2.8 and 4.72 +/- 2.91 (p<0.01), respectively. Before transplantation, metabolic encephalopathy was detected in 6 patients by EEG, whereas metabolic encephalopathy was detected in only 1 patient posttransplant. Posttransplantation PSG sleep duration (all stages) increased relative to pretransplant PSG values. Sleep latency and rapid eye movement latency were found to be reduced compared to the pretransplant values. Conclusion: This pilot study compared SDs in patients with pre- and post-LTx by combining the subjective and objective methods. Significant SD improvements were found at the 9th month.en_US
dc.identifier.citationGençdal, G., Türker, G., Gençdal, I. Y., Ekinci, B., Acar, Ş., Dinçkan, A., & Akyıldız, M. (2020). Assessment of sleep pattern and quality before and after liver transplantation using different methods. The Turkish Journal of Gastroenterology, 31(8), 581.en_US
dc.identifier.doi10.5152/tjg.2020.18809en_US
dc.identifier.endpage587en_US
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-85090894892en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage581en_US
dc.identifier.trdizinid413095en_US
dc.identifier.urihttps://doi.org/10.5152/tjg.2020.18809
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1132
dc.identifier.volume31en_US
dc.identifier.wosWOS:000571470300009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorDinçkan, Ayhan
dc.language.isoenen_US
dc.publisherAVESen_US
dc.relation.ispartofTURKISH JOURNAL OF GASTROENTEROLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSleep Disordersen_US
dc.subjectLiver Cirrhosisen_US
dc.subjectEEGen_US
dc.subjectPolysomnographyen_US
dc.subjectPSQIen_US
dc.subjectESSen_US
dc.titleAssessment of sleep pattern and quality before and after liver transplantation using different methodsen_US
dc.typeArticleen_US

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