Prevalence of obesity and metabolic syndrome in children with type 1 diabetes: A comparative assessment based on criteria established by the international diabetes federation, world health organisation and national cholesterol education program

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dc.authorscopusidCengiz Kara / 7006430279
dc.contributor.authorKoken, Ozlem Yayici
dc.contributor.authorKara, Cengiz
dc.contributor.authorYilmaz, Gulay Can
dc.contributor.authorAydin, Hasan Murat
dc.date.accessioned2020-08-30T20:06:14Z
dc.date.available2020-08-30T20:06:14Z
dc.date.issued2020
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionAYDIN, HASAN MURAT/0000-0001-7374-229X; Kara, Cengiz/0000-0002-8989-560Xen_US
dc.description.abstractObjective: To determine the prevalence of obesity and metabolic syndrome (MetS) in children and adolescents with type I diabetes (TI D) and to compare the widely accepted and used diagnostic criteria for MetS established by the International Diabetes Federation UDR World Health Organisation (WHO) and National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATPIII). Methods: We conducted a descriptive, cross sectional study including T1D patients between 8-18 years of age. The three sets of criteria were used to determine the prevalence of MetS and findings compared. Risk factors related to MetS were extracted from hospital records. Results: The study included 200 patients with T1D (52 % boys). Of these, 18 % (n = 36) were overweight/obese (body mass index percentile 85%). MetS prevalence was 10.5 %, 8.5% and 13.5% according to IDF, WHO and NCEP criteria, respectively. There were no statistically significant differences in age, gender, family history of T1D and T2D, pubertal stage, duration of diabetes, hemoglobin Al c levels and daily insulin doses between patients with or without MetS. In the overweight or obese T1D patients, the prevalence of MetS was 44.4 %, 38.8% and 44.4% according to IDF, WHO and NCEP-ATPIII criteria, respectively. Conclusion: Obesity prevalence in the T1D cohort was similar to that of the healthy population of the same age. Prevalence of MetS was higher in children and adolescents with TI D compared to the obese population in Turkey. The WHO criteria include microvascular complications which are rare in childhood and the NCEP criteria do not include a primary criterion while diagnosing non-obese patients according to waist circumference as MetS because the existence of diabetes is considered as a direct criterion. Our study suggests that IDF criteria which allows the diagnosis of MetS with obesity and have accepted criteria for the childhood are more suitable for the diagnosis of MetS in children and adolescents with T1D.en_US
dc.identifier.citationKoken, O. Y., Kara, C., Yilmaz, G. C., & Aydin, H. M. (2020). Prevalence of Obesity and Metabolic Syndrome in Children with Type 1 Diabetes: A Comparative Assessment Based on Criteria Established by the International Diabetes Federation, World Health Organisation and National Cholesterol Education Program. JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, 12(1), 55–62. https://doi.org/10.4274/jcrpe.galenos.2019.2019.0048en_US
dc.identifier.doi10.4274/jcrpe.galenos.2019.2019.0048en_US
dc.identifier.endpage62en_US
dc.identifier.issn1308-5727en_US
dc.identifier.issn1308-5735en_US
dc.identifier.issue1en_US
dc.identifier.pmid31434460en_US
dc.identifier.scopus2-s2.0-85082145193en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage55en_US
dc.identifier.trdizinid363348en_US
dc.identifier.urihttps://doi.org/10.4274/jcrpe.galenos.2019.2019.0048
dc.identifier.urihttps://hdl.handle.net/20.500.12713/435
dc.identifier.volume12en_US
dc.identifier.wosWOS:000521073900006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKara, Cengizen_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofJournal of Clinical Research In Pediatric Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectType 1 Diabetesen_US
dc.subjectMetabolic Syndromeen_US
dc.subjectDouble Diabetesen_US
dc.subjectPrevalenceen_US
dc.titlePrevalence of obesity and metabolic syndrome in children with type 1 diabetes: A comparative assessment based on criteria established by the international diabetes federation, world health organisation and national cholesterol education programen_US
dc.typeArticleen_US

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