Sodium fluorescein-guided brain tumor surgery under the YELLOW-560-nm surgical microscope filter in pediatric age group: feasibility and preliminary results

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dc.authoridBurcu Göker / 0000-0002-6084-8690
dc.authoridTalat Kırış / 0000-0002-2985-3758
dc.authorscopusidBurcu Göker / 15070388600
dc.authorscopusidTalat Kırış / 6602747157
dc.authorwosidBurcu Göker / JVN-8891-2024
dc.authorwosidTalat Kırış / AAP-4665-2020
dc.contributor.authorGöker, Burcu
dc.contributor.authorKırış, Talat
dc.date.accessioned2020-08-30T20:06:57Z
dc.date.available2020-08-30T20:06:57Z
dc.date.issued2019
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionKiris, Talat/0000-0002-2985-3758en_US
dc.descriptionGoker, Burcu ; Kiris, Talat (isu author)
dc.description.abstractObjectiveTo evaluate the feasibility and safety of sodium fluorescein (Na-Fl)-guided surgery with the use of the PENTERO 900 surgical microscope (Carl Zeiss, Meditec, Oberkochen, Germany) equipped with the YELLOW-560-nm filter and low-dose Na-Fl (2mg/kg) in pediatric brain tumor surgery.MethodsThe study included 23 pediatric patients with various intracranial pathologies, who underwent Na-Fl-guided surgery between April 2015 and February 2018. Clinical features, surgical observations, extent of resection, and tumor histopathology were retrospectively analyzed. The use of YELLOW-560-nm filter was found helpful if the discrimination of the pinkish brain tissue and bright yellow stained tumor tissue was clear. Otherwise, it was described as not helpful.ResultsThere were 11 female and 12 male patients with a mean age of 9.4years. There were 7 brain stem/tectal plate gliomas, 6 supratentorial tumors, 4 intraventricular tumors, 2 pineal tumors, 2 infratentorial tumors, 1 clivus tumor, and 1 tumor with supra- and infratentorial extensions in the current series. Na-Fl was found helpful by means of the tumor demarcation in 20 instances (87%). In 11 of these 20 operations (55%), a total resection was achieved regardless of the tumor pathology. A subtotal resection was achieved in the remaining 9 patients (45%). No adverse events or side effects were encountered with regard to Na-Fl use.ConclusionNa-Fl guidance with the use of the YELLOW-560 filter is safe and effective during brain tumor surgery in pediatric age group.en_US
dc.identifier.citationGoker, B., & Kiris, T. (2019). Sodium fluorescein-guided brain tumor surgery under the YELLOW-560-nm surgical microscope filter in pediatric age group: feasibility and preliminary results. CHILDS NERVOUS SYSTEM, 35(3), 429–435. https://doi.org/10.1007/s00381-018-04037-4en_US
dc.identifier.doi10.1007/s00381-018-04037-4en_US
dc.identifier.endpage435en_US
dc.identifier.issn0256-7040en_US
dc.identifier.issn1433-0350en_US
dc.identifier.issue3en_US
dc.identifier.pmid30610485en_US
dc.identifier.scopus2-s2.0-85059552800en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage429en_US
dc.identifier.urihttps://doi.org/10.1007/s00381-018-04037-4
dc.identifier.urihttps://hdl.handle.net/20.500.12713/663
dc.identifier.volume35en_US
dc.identifier.wosWOS:000459157800006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGöker, Burcuen_US
dc.institutionauthorKırış, Talaten_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofChilds Nervous Systemen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSodium Fluoresceinen_US
dc.subjectSurgical Microscopeen_US
dc.subjectYellow 560en_US
dc.subjectPediatricen_US
dc.subjectBrain Tumoren_US
dc.subjectFluorescence-Guided Surgeryen_US
dc.titleSodium fluorescein-guided brain tumor surgery under the YELLOW-560-nm surgical microscope filter in pediatric age group: feasibility and preliminary resultsen_US
dc.typeArticleen_US

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