A new alternative approach to management of acute phase Peyronie's disease: low intensity extracorporeal shockwave therapy and platelet-rich plasma

Basit Öğe Kaydı
dc.contributor.authorKarakose, Ayhan
dc.contributor.authorYitgin, Yasin
dc.date.accessioned2024-05-19T14:46:11Z
dc.date.available2024-05-19T14:46:11Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractBACKGROUND: The aim of this study was to investigate the efficacy, safety, and outcomes of the combination of low intensity external shock wave therapy (Li-ESWT) and platelet-rich plasma (PRP) therapy in acute phase Peyronie's disease (PD). METHODS: The datas of patients admitted with acute phase Peyronie's between January 2014 and January 2022 were reviewed retrospectively. In total, we included total 159 patients who used combination of vitamin E 600 mg/day plus colchicine 1.5 mg/day plus oral daily 5 mg tadalafil (N.=77) in group 1 and received Li-ESWT+PRP combination therapy plus oral daily 5 mg tadalafil (N.=82) in group 2. We noted characteristics of fibrous plaques, pain status, penile curvature degree, and erectile function parameters. All patients were visited at the 3rd and 12th months after the treatment. RESULTS: Preoperative demographic characteristics were similar in the two groups. There was a statistically significant improvement in the mean plaque size, penile curvature degree, IIEF-5 and VAS scores in the intervention group after the treatment. Ecchymosis and hematoma were not observed at the injection site and Li-ESWT application areas in the intervention group. No local or systemic drug reactions were noted in either group. CONCLUSIONS: Combination of Li-ESWT and PRP are highly effective and safety to early treatment in the acute phase PD.en_US
dc.identifier.doi10.23736/S2724-6051.23.05458-7
dc.identifier.issn2724-6051
dc.identifier.issn2724-6442
dc.identifier.pmid38093617en_US
dc.identifier.urihttps://doi.org10.23736/S2724-6051.23.05458-7
dc.identifier.urihttps://hdl.handle.net/20.500.12713/5465
dc.identifier.wosWOS:001145843200001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherEdizioni Minerva Medicaen_US
dc.relation.ispartofMinerva Urology and Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectPenile Indurationen_US
dc.subjectPlatelet-Rich Plasmaen_US
dc.subjectVisual Analog Scaleen_US
dc.titleA new alternative approach to management of acute phase Peyronie's disease: low intensity extracorporeal shockwave therapy and platelet-rich plasmaen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu