Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Galenos Publ House
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
In cardiooncology practice, early cardiotoxicity refers to an emerging subclinical myocardial dysfunction/injury in response to certain chemotherapeutic regimens. This condition can progress to overt cardiotoxicity in time and hence warrants proper and timely diagnostic and preventive strategies. Current diagnostic strategies for early cardiotoxicity are largely based on conventional biomarkers and certain echocardiographic indices. However, a significant gap still exists in this setting, warranting further strategies to improve diagnosis and overall prognosis in cancer survivors. Copeptin (surrogate marker of the arginine vasopressine axis) might serve as a promising adjunctive guide for the timely detection, risk stratification, and management of early cardiotoxicity on top of conventional strategies largely due to its multifaceted pathophysiological implications in the clinical setting. This work aims to focus on serum copeptin as a marker of early cardiotoxicity and its general clinical implications in patients with cancer.
Açıklama
Anahtar Kelimeler
Arginine-Vasopressin Increases, Left-Ventricular Dysfunction, High-Dose Chemotherapy, Long-Term Survival, Induced Cardiotoxicity, Prognostic Value, Stable Peptide, Takotsubo Cardiomyopathy, Cancer-Patients, Troponin-I
Kaynak
Balkan Medical Journal
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
40
Sayı
2
