Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications

dc.contributor.authorYalta, Kenan
dc.contributor.authorYetkin, Ertan
dc.contributor.authorYalta, Tuelin
dc.date.accessioned2024-05-19T14:51:24Z
dc.date.available2024-05-19T14:51:24Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractIn cardiooncology practice, early cardiotoxicity refers to an emerging subclinical myocardial dysfunction/injury in response to certain chemotherapeutic regimens. This condition can progress to overt cardiotoxicity in time and hence warrants proper and timely diagnostic and preventive strategies. Current diagnostic strategies for early cardiotoxicity are largely based on conventional biomarkers and certain echocardiographic indices. However, a significant gap still exists in this setting, warranting further strategies to improve diagnosis and overall prognosis in cancer survivors. Copeptin (surrogate marker of the arginine vasopressine axis) might serve as a promising adjunctive guide for the timely detection, risk stratification, and management of early cardiotoxicity on top of conventional strategies largely due to its multifaceted pathophysiological implications in the clinical setting. This work aims to focus on serum copeptin as a marker of early cardiotoxicity and its general clinical implications in patients with cancer.en_US
dc.identifier.doi10.4274/balkanmedj.galenos.2023.2023-2-14
dc.identifier.endpage92en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue2en_US
dc.identifier.pmid36883738en_US
dc.identifier.scopus2-s2.0-85149533385en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage82en_US
dc.identifier.urihttps://doi.org10.4274/balkanmedj.galenos.2023.2023-2-14
dc.identifier.urihttps://hdl.handle.net/20.500.12713/5935
dc.identifier.volume40en_US
dc.identifier.wosWOS:000952522000003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectArginine-Vasopressin Increasesen_US
dc.subjectLeft-Ventricular Dysfunctionen_US
dc.subjectHigh-Dose Chemotherapyen_US
dc.subjectLong-Term Survivalen_US
dc.subjectInduced Cardiotoxicityen_US
dc.subjectPrognostic Valueen_US
dc.subjectStable Peptideen_US
dc.subjectTakotsubo Cardiomyopathyen_US
dc.subjectCancer-Patientsen_US
dc.subjectTroponin-Ien_US
dc.titleSerum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implicationsen_US
dc.typeReview Articleen_US

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