Lack of right ventricular hypertrophy is associated with right heart failure in patients with left ventricular failure
Yükleniyor...
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Presence of right heart failure (RHF) is associated with a worse prognosis in patients with left ventricular failure (LVF). While the cause of RHF secondary to LVF is multifactorial, an increased right ventricular (RV) afterload is believed as the major cause of RHF. However, data are scarce on the adaptive responses of the RV in patients with LVF. Our aim was to understand the relationship of right ventricular hypertrophy (RVH) with RHF and RV systolic and diastolic properties in patients with LVF. 55 patients with a left ventricular ejection fraction of 40% or less were included in the present study. A comprehensive two-dimensional transthoracic echocardiographic examination was done to all participants. 12 patients (21.8%) had RHF, and patients with RHF had a signifcantly lower right ventricular free wall thickness (RVFWT) as compared to patients without RHF (5.3±1.7 mm vs. 6.6±0.9 mm, p=0.02) and the diference remained statistically signifcant after adjusting for confounders (?x?:1.34 mm, p=0.002). RVFWT had a statistically signifcant correlation with tricuspid annular plane systolic excursion (r=0.479, p<0.001) and tricuspid annular lateral systolic velocity (r=0.360, p=0.007), but not with the indices of the RV diastolic function. None of the patients with concentric RVH had RHF, while 22.2% of patients with eccentric RVH and 66.7% of patients without RVH had RHF (p<0.01 as compared to patients with concentric RVH). In patients with left ventricular systolic dysfunction, absence of RVH was associated with worse RV systolic performance and a signifcantly higher incidence of RHF
Açıklama
Anahtar Kelimeler
Right Heart Failure, Right Ventricular Hypertrophy, Right Ventricular Free Wall Thickness, Left Ventricular Failure
Kaynak
Heart and Vessels
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
37
Sayı
5
Künye
Naser A, Güvenç TS, Isgandarov K, Ekmekçi A, Gündüz S, Çetin Güvenç R, Şahin M. Lack of right ventricular hypertrophy is associated with right heart failure in patients with left ventricular failure. Heart Vessels. 2022 Apr 26. doi: 10.1007/s00380-022-02075-2. Epub ahead of print. PMID: 35471461.
