Lack of right ventricular hypertrophy is associated with right heart failure in patients with left ventricular failure

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dc.authoridMüslüm Şahin / 0000-0003-4976-6720en_US
dc.authorscopusidMüslüm Şahin / 41862126900
dc.authorwosidMüslüm Şahin / DNT-9358-2022en_US
dc.contributor.authorNaser, Abdulrahman
dc.contributor.authorIsgandarov, Khagani
dc.contributor.authorGüvenç, Tolga Sinan
dc.contributor.authorEkmekçi, Ahmet
dc.contributor.authorGündüz, Sabahattin
dc.contributor.authorGüvenç, Rengin Çetin
dc.contributor.authorŞahin, Müslüm
dc.date.accessioned2022-05-23T08:13:21Z
dc.date.available2022-05-23T08:13:21Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesien_US
dc.description.abstractPresence of right heart failure (RHF) is associated with a worse prognosis in patients with left ventricular failure (LVF). While the cause of RHF secondary to LVF is multifactorial, an increased right ventricular (RV) afterload is believed as the major cause of RHF. However, data are scarce on the adaptive responses of the RV in patients with LVF. Our aim was to understand the relationship of right ventricular hypertrophy (RVH) with RHF and RV systolic and diastolic properties in patients with LVF. 55 patients with a left ventricular ejection fraction of 40% or less were included in the present study. A comprehensive two-dimensional transthoracic echocardiographic examination was done to all participants. 12 patients (21.8%) had RHF, and patients with RHF had a signifcantly lower right ventricular free wall thickness (RVFWT) as compared to patients without RHF (5.3±1.7 mm vs. 6.6±0.9 mm, p=0.02) and the diference remained statistically signifcant after adjusting for confounders (?x?:1.34 mm, p=0.002). RVFWT had a statistically signifcant correlation with tricuspid annular plane systolic excursion (r=0.479, p<0.001) and tricuspid annular lateral systolic velocity (r=0.360, p=0.007), but not with the indices of the RV diastolic function. None of the patients with concentric RVH had RHF, while 22.2% of patients with eccentric RVH and 66.7% of patients without RVH had RHF (p<0.01 as compared to patients with concentric RVH). In patients with left ventricular systolic dysfunction, absence of RVH was associated with worse RV systolic performance and a signifcantly higher incidence of RHFen_US
dc.identifier.citationNaser A, Güvenç TS, Isgandarov K, Ekmekçi A, Gündüz S, Çetin Güvenç R, Şahin M. Lack of right ventricular hypertrophy is associated with right heart failure in patients with left ventricular failure. Heart Vessels. 2022 Apr 26. doi: 10.1007/s00380-022-02075-2. Epub ahead of print. PMID: 35471461.en_US
dc.identifier.doi10.1007/s00380-022-02075-2en_US
dc.identifier.issn0910-8327en_US
dc.identifier.issue5en_US
dc.identifier.pmid35471461en_US
dc.identifier.scopus2-s2.0-85128877885en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttp://doi.org/10.1007/s00380-022-02075-2
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2704
dc.identifier.volume37en_US
dc.identifier.wosWOS:000787626600001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorŞahin, Müslüm
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofHeart and Vesselsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRight Heart Failureen_US
dc.subjectRight Ventricular Hypertrophyen_US
dc.subjectRight Ventricular Free Wall Thicknessen_US
dc.subjectLeft Ventricular Failureen_US
dc.titleLack of right ventricular hypertrophy is associated with right heart failure in patients with left ventricular failureen_US
dc.typeArticleen_US

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