The association of BMI and sarcopenia with survival in patients with glioblastoma multiforme
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: The association between obesity and sarcopenia (via temporal muscle thickness) with overall survival (OS) has been evaluated in several glioblastoma multiforme studies, however, the data are inconclusive. Methods: The authors conducted meta-analyses via the generic inverse-variance method with a random-effects model. Results: In the pooled analysis of five studies, including 973 patients, patients with lower temporal muscle thickness had significantly decreased OS (HR: 1.62, 95% CI: 1.16-2.28, p = 0.005). The pooled analysis of five studies, including 2131 patients, demonstrated decreased OS in patients with lower BMI compared with patients with obesity (HR: 1.45, 95% CI: 1.12-1.88, p = 0.005). Conclusion: Readily available body composition parameters could be used for prognosis prediction and to aid in treatment decisions in patients with glioblastoma multiforme.
Açıklama
Anahtar Kelimeler
Glioblastoma Multiforme, Obesity, Prognosis, Sarcopenia, Temporal Muscle Thickness
Kaynak
FUTURE ONCOLOGY
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
Sayı
Künye
Guven, D. C., Aksun, M. S., Cakir, I. Y., Kilickap, S., & Kertmen, N. (2021). The association of BMI and sarcopenia with survival in patients with glioblastoma multiforme. Future Oncology, (0).
