The association of BMI and sarcopenia with survival in patients with glioblastoma multiforme

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dc.authoridSaadettin Kılıçkap / 0000-0003-1637-7390
dc.authorscopusidSaadettin Kılıçkap / 8665552100
dc.authorwosidSaadettin Kılıçkap / DXP-4273-2022
dc.contributor.authorGüven, Deniz Can
dc.contributor.authorAksun, Melek Seren
dc.contributor.authorÇakır, İbrahim Yahya
dc.contributor.authorKılıçkap, Saadettin
dc.contributor.authorKertmen, Neyran
dc.date.accessioned2021-09-01T06:46:12Z
dc.date.available2021-09-01T06:46:12Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: The association between obesity and sarcopenia (via temporal muscle thickness) with overall survival (OS) has been evaluated in several glioblastoma multiforme studies, however, the data are inconclusive. Methods: The authors conducted meta-analyses via the generic inverse-variance method with a random-effects model. Results: In the pooled analysis of five studies, including 973 patients, patients with lower temporal muscle thickness had significantly decreased OS (HR: 1.62, 95% CI: 1.16-2.28, p = 0.005). The pooled analysis of five studies, including 2131 patients, demonstrated decreased OS in patients with lower BMI compared with patients with obesity (HR: 1.45, 95% CI: 1.12-1.88, p = 0.005). Conclusion: Readily available body composition parameters could be used for prognosis prediction and to aid in treatment decisions in patients with glioblastoma multiforme.en_US
dc.identifier.citationGuven, D. C., Aksun, M. S., Cakir, I. Y., Kilickap, S., & Kertmen, N. (2021). The association of BMI and sarcopenia with survival in patients with glioblastoma multiforme. Future Oncology, (0).en_US
dc.identifier.doi10.2217/fon-2021-0681en_US
dc.identifier.issn1479-6694en_US
dc.identifier.issn1744-8301en_US
dc.identifier.pmid34409854en_US
dc.identifier.scopus2-s2.0-85118411396en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2015
dc.identifier.wosWOS:000686230400001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKılıçkap, Saadettin
dc.language.isoenen_US
dc.relation.ispartofFUTURE ONCOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlioblastoma Multiformeen_US
dc.subjectObesityen_US
dc.subjectPrognosisen_US
dc.subjectSarcopeniaen_US
dc.subjectTemporal Muscle Thicknessen_US
dc.titleThe association of BMI and sarcopenia with survival in patients with glioblastoma multiformeen_US
dc.typeArticleen_US

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