Long-term outcomes of carinal sleeve resection in non-small cell lung cancer

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dc.authoridCelalettin İbrahim Kocatürk / 0000-0001-9368-1009
dc.authorscopusidCelalettin İbrahim Kocatürk / 8535429200
dc.authorwosidCelalettin İbrahim Kocatürk / GDC-5922-2022
dc.contributor.authorSezen, Celal Buğra
dc.contributor.authorKocatürk, Celalettin İbrahim
dc.contributor.authorBilen, Salih
dc.contributor.authorKalafat, Cem Emrah
dc.contributor.authorCansever, Levent
dc.contributor.authorDinçer, Seyyit İbrahim
dc.contributor.authorBedirhan, Mehmet Ali
dc.date.accessioned2020-08-30T20:06:15Z
dc.date.available2020-08-30T20:06:15Z
dc.date.issued2020
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground Carinal resections for non-small cell lung cancer (NSCLC) invading the carina are challenging cases that require a therapeutic strategy. The aim of this study was to compare the oncologic outcomes and complications of patients who underwent carinal resection. Methods Sixty-four patients who underwent carinal resection between 2005 and 2016 were evaluated. Data were retrospectively reviewed for indications, complications, and factors influencing long-term survival. Results The study included 51 patients (79.7%) who underwent sleeve pneumonectomy (sP) and 13 patients who underwent carinal sleeve lobectomy (csL) as a curative therapy. Nine patients (14.1%) received induction chemotherapy. Complications were observed in 31 patients (48.8%), including 24 patients (47.1%) in the sP group and 7 patients (53.8%) in the csL group ( p = 0.662). Six patients (9.4%) developed bronchopleural fistula. The 30-day mortality rate was 10.9% ( n = 7). The 5- and 10-year survival rates were 42.2 and 23.1%, respectively. N2 and R1 were identified as factors affecting survival ( p = 0.029 and p = 0.047). Conclusion Carinal resections have acceptable morbidity, mortality, and long-term survival outcomes in central NSCLC. The main factors affecting survival are complete resection and nodal status. The results of csL were similar to those of sP. Therefore, we believe that csL should be performed in all eligible patients.en_US
dc.identifier.citationSezen, C. B., Kocaturk, C. I., Bilen, S., Kalafat, C. E., Cansever, L., Dincer, S. I., & Bedirhan, M. A. (2020). Long-term outcomes of carinal sleeve resection in non-small cell lung cancer. The Thoracic and cardiovascular surgeon, 68(02), 190-198.en_US
dc.identifier.doi10.1055/s-0039-1679959en_US
dc.identifier.endpage197en_US
dc.identifier.issn0171-6425en_US
dc.identifier.issn1439-1902en_US
dc.identifier.issue2en_US
dc.identifier.pmid30808024en_US
dc.identifier.scopus2-s2.0-85081022446en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage190en_US
dc.identifier.urihttps://doi.org/10.1055/s-0039-1679959
dc.identifier.urihttps://hdl.handle.net/20.500.12713/439
dc.identifier.volume68en_US
dc.identifier.wosWOS:000518614600014en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKocatürk, Celalettin İbrahimen_US
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofThoracic and Cardiovascular Surgeonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCarinal Resectionen_US
dc.subjectNon-Small Cell Lung Canceren_US
dc.subjectCentralen_US
dc.subjectTumorsen_US
dc.subjectLobectomyen_US
dc.titleLong-term outcomes of carinal sleeve resection in non-small cell lung canceren_US
dc.typeArticleen_US

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