Concomitant autoimmune diseases in patients with sarcoidosis in Turkey

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dc.authoridŞenol Kobak / 0000-0001-8270-640Xen_US
dc.authorscopusidŞenol Kobak / 12782228700
dc.authorwosidŞenol Kobak / AAO-2482-2020
dc.contributor.authorYıldız, Fidan
dc.contributor.authorKobak, Şenol
dc.contributor.authorSemiz, Hüseyin
dc.contributor.authorOrman, Mehmet
dc.date.accessioned2020-08-30T20:06:10Z
dc.date.available2020-08-30T20:06:10Z
dc.date.issued2020
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives: This study aims to determine the frequency and characteristics of autoimmune diseases associated with sarcoidosis patients. Patients and methods: The study included 131 sarcoidosis patients (36 males, 95 females; mean age 46.1 years; range, 20 to 82 years). Demographic, clinical, laboratory and radiological data of patients were evaluated retrospectively. The characteristics of autoimmune diseases associated with sarcoidosis (sarcoidosis-overlap group) patients and isolated sarcoidosis (isolated sarcoidosis group) were analyzed and compared. Results: Concomitant autoimmune diseases were detected in 15 (11.5%) (5 males, 10 females; mean age 50.8 years; range, 26 to 58 years) of the 131 patients with sarcoidosis and their mean disease duration was three months (range, 1 to 30 months). When compared with isolated sarcoidosis patients, more hand finger joint involvement, rheumatoid factor (RF) positivity, higher erythrocyte sedimentation rate (ESR) and less nonsteroidal anti-inflammatory drugs (NSAIDs) usage were found in the sarcoidosis-overlap group (p= 0.035, p=0.049, p= 0.015, p=0.018, respectively). There were no statistically significant differences between the two groups when evaluated for demographic, clinical parameters and disease-modifying antirheumatic drugs usage. Conclusion: Concomitant autoimmune diseases in patients with sarcoidosis may be rarely seen. These patients are characterized with more hand finger joint involvement, RF positivity, higher ESR and less NSAIDs usage. Multicenter, prospective studies involving large numbers of patients are needed to understand whether the association of sarcoidosis-autoimmune diseases is based only on coincidence or on a common etiopathogenesis.en_US
dc.identifier.citationYildiz, F., Kobak, Ş., Semİz, H., & Orman, M. (2020). Concomitant autoimmune diseases in patients with sarcoidosis in Turkey. Archives of Rheumatology, 35(2), 259.en_US
dc.identifier.doi10.46497/ArchRheumatol.2020.7649en_US
dc.identifier.endpage263en_US
dc.identifier.issn2148-5046en_US
dc.identifier.issn1309-0283en_US
dc.identifier.issue2en_US
dc.identifier.pmid32851376en_US
dc.identifier.scopus2-s2.0-85086658051en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage259en_US
dc.identifier.trdizinid363379en_US
dc.identifier.urihttps://doi.org/10.46497/ArchRheumatol.2020.7649
dc.identifier.urihttps://hdl.handle.net/20.500.12713/399
dc.identifier.volume35en_US
dc.identifier.wosWOS:000538169900014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKobak, Şenolen_US
dc.language.isoenen_US
dc.publisherTurkish League Against Rheumatismen_US
dc.relation.ispartofArchives of Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAutoimmune Diseasesen_US
dc.subjectConcomitanten_US
dc.subjectSarcoidosisen_US
dc.titleConcomitant autoimmune diseases in patients with sarcoidosis in Turkeyen_US
dc.typeArticleen_US

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