Comparison of similar cells: mesenchymal stromal cells and fibroblasts

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dc.authoridBurcu Uğurlu / 0000-0001-7142-4431en_US
dc.authoridErdal Karaöz / 0000-0002-9992-833X
dc.authorscopusidBurcu Uğurlu / 57194496503
dc.authorwosidBurcu Uğurlu / AAC-9198-2021
dc.authorwosidErdal Karaöz / IXE-6677-2023
dc.contributor.authorUğurlu, Burcu
dc.contributor.authorKaraöz, Erdal
dc.date.accessioned2020-10-19T11:42:24Z
dc.date.available2020-10-19T11:42:24Z
dc.date.issued2020en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractAlmost from all organs, both mesenchymal stromal cells and fibroblasts can be isolated. Mesenchymal stromal cells (MSCs) are the most preferred cellular therapeutic agents with the regenerative potential, and fibroblasts are one of the most abundant cell types with the ability to maintain homeostasis. Because of the promising properties of MSCs, they have been well studied and their differentiation potentials, immunomodulatory potentials, gene expression profiles are identified. It has been observed that fibroblasts and mesenchymal stromal cells have similar morphology, gene expression patterns, surface markers, proliferation, differentiation, and immunomodulatory capacities. Thus, it is hard to distinguish these two cell types. Epigenetic signatures, i.e., methylation patterns of cells, are the only usable promising difference between them. Such significant similarities show that these two cells may be related to each other.en_US
dc.identifier.citationUgurlu, B., & Karaoz, E. (2020). Comparison of similar cells: Mesenchymal stromal cells and fibroblasts. Acta Histochemica, 122(8), 151634.en_US
dc.identifier.doi10.1016/j.acthis.2020.151634en_US
dc.identifier.issn0065-1281en_US
dc.identifier.issue8en_US
dc.identifier.pmid33059115en_US
dc.identifier.scopus2-s2.0-85092418933en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1016/j.acthis.2020.151634
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1144
dc.identifier.volume122en_US
dc.identifier.wosWOS:000593955400010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUğurlu, Burcu
dc.institutionauthorKaraöz, Erdal
dc.language.isoenen_US
dc.publisherElsevier GmbHen_US
dc.relation.ispartofActa Histochemicaen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCell Surface Markersen_US
dc.subjectDifferentiationen_US
dc.subjectFibroblastsen_US
dc.subjectGene Expressionen_US
dc.subjectMesenchymal Stromal Cellsen_US
dc.subjectProliferationen_US
dc.titleComparison of similar cells: mesenchymal stromal cells and fibroblastsen_US
dc.typeReview Articleen_US

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