Analysis of Complications of a Neglected Disease: 13 Years of Experience with Liver Hydatid Cysts in a High-Volume Hospital

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dc.authorscopusidMustafa Azizoğlu / 58901683600
dc.authorwosidMustafa Azizoğlu / HKV-3601-2023
dc.contributor.authorAzizoğlu, Mustafa
dc.contributor.authorAydoğdu, Bahattin
dc.contributor.authorKamçı, Tahsin Onat
dc.contributor.authorArslan, Serkan
dc.contributor.authorBaşuguy, Erol
dc.contributor.authorBilici, Salim
dc.contributor.authorOkur, Mehmet Hanifi
dc.date.accessioned2025-06-04T10:47:17Z
dc.date.available2025-06-04T10:47:17Z
dc.date.issued2024
dc.departmentİstinye Üniversitesi, Lisansüstü Eğitim Enstitüsü, Sağlık Bilimleri, Kök Hücre ve Doku Mühendisliği Programı
dc.description.abstractBackground and Objectives: The aim of this study was to evaluate the clinical presentation, treatment outcomes, and complications associated with hepatic hydatid cysts in a pediatric population. Materials and Methods: This retrospective study analyzed 214 pediatric patients with liver hydatid cysts, focusing on clinical presentation, treatment outcomes, and associated complications. Patients were classified based on treatment modality, including non-operative management with albendazole, PAIR, and surgical intervention. This study compared cyst characteristics, recurrence rates, and complications such as cysto-biliary fistulas. Results: Among the patients, 68% (n = 145) had a single cyst and 86% (n = 184) were found to have isolated liver cysts. No significant statistical difference was observed between Group 1 and Group 2 in terms of age, gender, and basic laboratory values and general characteristics of the cysts, such as the lobe where the cyst was located, involvement of multiple organs, number of cysts, the state of cyst rupture, and recurrence; no statistically significant difference was found between the groups (p > 0.05 for each comparison). Cyst rupture incidence was 6%, and the average incidence of recurrence was 2%, with a surgical recurrence incidence of 3%. A total of 37 patients had a laparotomy, while 7 had laparoscopic surgery. In total, capitonnage was performed in 68 patients, omentopexy in 4, and cystostomy in 6. Consequently, among the treated patients (PAIR + surgery), the incidence of cysto-biliary fistula was 11%, anaphylaxis was 2%, surgical recurrence was 3%, and the incidence of reoperation (Clavien–Dindo ≥ 3) was 6%. The average follow-up period was 72 months, during which no mortality was observed. Conclusions: We identified key clinical outcomes related to both non-surgical treatments (cyst rupture and recurrence) and surgical groups (cysto-biliary fistulas, anaphylaxis, the need for reoperation, rupture, and recurrence). © 2024 by the authors.
dc.identifier.citationAzizoğlu, M., Aydogdu, B., Kamci, T. O., Arslan, S., Basuguy, E., Bilici, S., & Okur, M. H. (2024). Analysis of Complications of a Neglected Disease: 13 Years of Experience with Liver Hydatid Cysts in a High-Volume Hospital. Medicina, 60(10), 1696.
dc.identifier.doi10.3390/medicina60101696
dc.identifier.issn1010660X
dc.identifier.issue10
dc.identifier.pmid39459483
dc.identifier.scopusqualityQ1
dc.identifier.urihttp://dx.doi.org/10.3390/medicina60101696
dc.identifier.urihttps://hdl.handle.net/20.500.12713/7295
dc.identifier.volume60
dc.identifier.wosWOS:001343518300001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakScopus
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorAzizoğlu, Mustafa
dc.institutionauthoridMustafa Azizoğlu / 0009-0000-3563-1230
dc.language.isoen
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)
dc.relation.ispartofMedicina (Lithuania)
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectComplications Analysis
dc.subjectCysto-Biliary Fistula
dc.subjectEchinococcus Granulosus
dc.subjectLiver Hydatid Cyst
dc.titleAnalysis of Complications of a Neglected Disease: 13 Years of Experience with Liver Hydatid Cysts in a High-Volume Hospital
dc.typeArticle

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