Correlation Between Clinical and Histological Features of Dermatopathic Lymphadenopathy: Analysis of 39 Lymph Nodes

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dc.authoridAktaş, Ezgi/0000-0001-6634-2810
dc.authoridZemheri, Itır Ebru/0000-0003-0247-0332
dc.authorwosidAktaş, Ezgi/S-4737-2019
dc.authorwosidZemheri, Itır Ebru/JRY-6674-2023
dc.contributor.authorDemir, Damla
dc.contributor.authorIhvan, Aysenur
dc.contributor.authorAktas, Ezgi
dc.contributor.authorZemheri, Ebru
dc.contributor.authorZindanci, Ilkin
dc.date.accessioned2024-05-19T14:40:37Z
dc.date.available2024-05-19T14:40:37Z
dc.date.issued2024
dc.departmentİstinye Üniversitesien_US
dc.description.abstractBackground. Dermatopathic lymphadenopathy is a well-defined histopathological entity with an underestimated prevalence in the general population. Objective. The present study was conducted to analyze the characteristics of histologically diagnosed cases of dermatopathic lymphadenopathy at our unit. We also aimed to investigate any association between the clinical features of the patients and the histological findings. Methods. A total of 39 lymph node samples from 39 patients diagnosed with dermatopathic lymphadenopathy were included in this prospective cohort study. Results. Thirty-four (87%) patients had a dermatological disorder. The presence of paracortical eosinophils were significantly higher in patients with dermatological disorders (P = .001), while the presence of dilated sinuses was significantly more common in patients without a dermatological disorder (P = .035). The presence of dilated sinuses and medullary histiocytes were significantly more common in patients with lower body surface area involvement of the disease compared to the ones with a higher body surface area (P = .003, P = .034; respectively). Conclusion. Most of the patients included in the study had one of a broad spectrum of undiagnosed dermatological disorders. The clinical significance of the relation between histological and clinical findings in dermatopathic lymphadenopathy remains to be explained. Dermatopathic lymphadenopathy should always be considered in differential diagnoses of patients with persistent lymph node enlargement even when absolute dermatological disorders are not present. Since various skin disorders may be the cause of lymphadenopathy, performing a full-body examination before lymph node excision might prevent unneccessary procedures.en_US
dc.identifier.doi10.1177/10668969231173381
dc.identifier.endpage262en_US
dc.identifier.issn1066-8969
dc.identifier.issn1940-2465
dc.identifier.issue2en_US
dc.identifier.pmid37151027en_US
dc.identifier.scopus2-s2.0-85158911572en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage252en_US
dc.identifier.urihttps://doi.org10.1177/10668969231173381
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4989
dc.identifier.volume32en_US
dc.identifier.wosWOS:000983350300001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofInternational Journal of Surgical Pathologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectCutaneous Disordersen_US
dc.subjectDermatopathic Lymphadenopathyen_US
dc.subjectHistologyen_US
dc.titleCorrelation Between Clinical and Histological Features of Dermatopathic Lymphadenopathy: Analysis of 39 Lymph Nodesen_US
dc.typeArticleen_US

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