Does blood pressure variability affect hypertension development in pre-hypertensive patients?
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Oxford Academic
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Blood pressure variability (BPV) is associated with end organ damage and cardiovascular outcomes in hypertensive patients. Pre-hypertensive patients frequently develop hypertension (HT). The purpose of the present study was to evaluate the effect of BPV on the development of HT. Methods: Two hundred seven pre-hypertensive patients from the Cappadocia cohort were monitored over two years, and 24-h ambulatory blood pressure monitoring (24-h ABPM), office and home BP measurements were subsequently performed at four to six-month intervals. BPV was calculated as average real variability (ARV) from 24-h ABPM data, home and office BP measurements at first visit. The relationship was evaluated between baseline ARV and the development of HT. Results: HT was diagnosed in 25.60% of subjects. Baseline 24-h ABPM systolic blood pressure (SBP)ARV and diastolic blood pressure (DBP)ARV and home SBP ARV were significantly higher in patients who developed HT than the other patients (p 0.006, 0.001 and 0.006, respectively). Baseline 24h-ABPM SBPARV and home SBPARV exceeding the 90 th percentile were identified as parameters affecting development of HT at logistic regression analysis. Conclusion: In conclusion, our prospective observational cohort study showed that short-term BPV in particular can predict the development of HT in the pre-hypertensive population.
Açıklama
Anahtar Kelimeler
ABPM, BPV, Blood Pressure Variability, Hypertension Diagnosis, Prehypertension
Kaynak
American Journal of Hypertension
WoS Q Değeri
Q3
Scopus Q Değeri
N/A
Cilt
35
Sayı
1
Künye
Özkan, G., Ulusoy, Ş., Arıcı, M., Derici, Ü., Akpolat, T., Şengül, Ş., Yılmaz, R., Ertürk, Ş., Arınsoy, T., Değer, S. M., Erdem, Y., & Turkish Society of Hypertension and Renal Diseases (2021). Does blood pressure variability affect hypertension development in pre-hypertensive patients?. American journal of hypertension, hpab125. Advance online publication. https://doi.org/10.1093/ajh/hpab125
