Does blood pressure variability affect hypertension development in pre-hypertensive patients?

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dc.authoridTekin Akpolat / 0000-0003-3104-9205
dc.authorscopusidTekin Akpolat / 7004571672
dc.authorwosidTekin Akpolat / IAM-7772-2023
dc.contributor.authorÖzkan, Gülsüm
dc.contributor.authorUlusoy, Şükrü
dc.contributor.authorArıcı, Mustafa
dc.contributor.authorDerici, Ülver
dc.contributor.authorAkpolat, Tekin
dc.contributor.authorŞengül, Şule
dc.date.accessioned2021-08-09T08:34:02Z
dc.date.available2021-08-09T08:34:02Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Blood pressure variability (BPV) is associated with end organ damage and cardiovascular outcomes in hypertensive patients. Pre-hypertensive patients frequently develop hypertension (HT). The purpose of the present study was to evaluate the effect of BPV on the development of HT. Methods: Two hundred seven pre-hypertensive patients from the Cappadocia cohort were monitored over two years, and 24-h ambulatory blood pressure monitoring (24-h ABPM), office and home BP measurements were subsequently performed at four to six-month intervals. BPV was calculated as average real variability (ARV) from 24-h ABPM data, home and office BP measurements at first visit. The relationship was evaluated between baseline ARV and the development of HT. Results: HT was diagnosed in 25.60% of subjects. Baseline 24-h ABPM systolic blood pressure (SBP)ARV and diastolic blood pressure (DBP)ARV and home SBP ARV were significantly higher in patients who developed HT than the other patients (p 0.006, 0.001 and 0.006, respectively). Baseline 24h-ABPM SBPARV and home SBPARV exceeding the 90 th percentile were identified as parameters affecting development of HT at logistic regression analysis. Conclusion: In conclusion, our prospective observational cohort study showed that short-term BPV in particular can predict the development of HT in the pre-hypertensive population.en_US
dc.identifier.citationÖzkan, G., Ulusoy, Ş., Arıcı, M., Derici, Ü., Akpolat, T., Şengül, Ş., Yılmaz, R., Ertürk, Ş., Arınsoy, T., Değer, S. M., Erdem, Y., & Turkish Society of Hypertension and Renal Diseases (2021). Does blood pressure variability affect hypertension development in pre-hypertensive patients?. American journal of hypertension, hpab125. Advance online publication. https://doi.org/10.1093/ajh/hpab125en_US
dc.identifier.doi10.1093/ajh/hpab125en_US
dc.identifier.endpage78en_US
dc.identifier.issue1en_US
dc.identifier.pmid34351385en_US
dc.identifier.scopus2-s2.0-85123323495en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage73en_US
dc.identifier.urihttps://doi.org/10.1093/ajh/hpab125
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1983
dc.identifier.volume35en_US
dc.identifier.wosWOS:000743294300011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAkpolat, Tekin
dc.language.isoenen_US
dc.publisherOxford Academicen_US
dc.relation.ispartofAmerican Journal of Hypertensionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectABPMen_US
dc.subjectBPVen_US
dc.subjectBlood Pressure Variabilityen_US
dc.subjectHypertension Diagnosisen_US
dc.subjectPrehypertensionen_US
dc.titleDoes blood pressure variability affect hypertension development in pre-hypertensive patients?en_US
dc.typeArticleen_US

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