Relationship between fragmented QRS complex and long-term cardiovascular outcome in patients with essential hypertension

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dc.authoridAnıl Şahin / 0000-0003-1956-2348en_US
dc.authorscopusidAnıl Şahin / 57218563931
dc.authorwosidAnıl Şahin / AFS-8068-2022
dc.contributor.authorAltunova, Mehmet
dc.contributor.authorPusuroğlu, Hamdi
dc.contributor.authorDemir, Ali Rıza
dc.contributor.authorYılmaz, Emre
dc.contributor.authorÇizgici, Ahmet Yaşar
dc.contributor.authorErtürk, Mehmet
dc.contributor.authorŞahin, Ahmet Anıl
dc.contributor.authorKarakayalı, Muammer
dc.date.accessioned2022-06-24T08:05:32Z
dc.date.available2022-06-24T08:05:32Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: In patients with essential hypertension, fragmented QRS has been associated with many remodeling components that might lead to adverse cardiovascular effects. This study aimed to evaluate the relationship between fragmented QRS and adverse events and its potential long-term prognostic value. Methods: The patients with essential hypertension were divided into two groups according to the presence of fragmented QRS: fragmented QRS (+) and fragmented QRS (?). During long-term follow-up, the relationship of fragmented QRS to coronary artery disease, congestive heart failure, stroke, cardiovascular death, all-cause death, and major adverse cardiovascular and cerebrovascular events was evaluated. Results: The study group included 542 patients with essential hypertension. Fragmented QRS on ECG was observed in 224 (41.3%) patients. Considering the incidence rates at the end of 5.6 ± 1.3 years’ follow-up, the total incidence rate of major adverse cardiovascular and cerebrovascular events (P < .001), coronary artery disease (P < .001), and congestive heart failure (P < .001) were higher in patients with fragmented QRS. No significant difference was observed between the two groups in terms of stroke (P=.734), cardiovascular death (P=1), and all-cause death (P=.574). As a result of multiple cox regression analysis, fragmented QRS (P=.005) was identified as an independent predictor for major adverse cardiovascular and cerebrovascular events development. Conclusion: In patients with hypertension, the presence of fragmented QRS was found as an independent predictor for major adverse cardiovascular and cerebrovascular events development.en_US
dc.identifier.citationAltunova M, Püşüroğlu H, Karakayalı M, Şahin AA, Demir AR, Yılmaz E, Çizgici AY, Ertürk M. Relationship Between Fragmented QRS Complex and Long-Term Cardiovascular Outcome in Patients with Essential Hypertension. Anatol J Cardiol. 2022 Jun;26(6):442-449. doi: 10.5152/AnatolJCardiol.2022.1322. PMID: 35703480.en_US
dc.identifier.doi10.5152/AnatolJCardiol.2022.1322en_US
dc.identifier.endpage449en_US
dc.identifier.issn2149-2263en_US
dc.identifier.issue6en_US
dc.identifier.pmid35703480en_US
dc.identifier.scopus2-s2.0-85132451741en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage442en_US
dc.identifier.trdizinid523737en_US
dc.identifier.urihttp://doi.org/10.5152/AnatolJCardiol.2022.1322
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2938
dc.identifier.volume26en_US
dc.identifier.wosWOS:000965507600004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Society of Cardiologyen_US
dc.relation.ispartofThe Anatolian Journal of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEssential Hypertensionen_US
dc.subjectFragmented QRSen_US
dc.subjectMajor Adverse Cardiovascular and Cerebrovascular Eventsen_US
dc.subjectMortalityen_US
dc.titleRelationship between fragmented QRS complex and long-term cardiovascular outcome in patients with essential hypertensionen_US
dc.typeArticleen_US

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