Clinicopathological evaluation of 15 Ectopic adrenal tissues
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Academy of Medical Sciences of I.R. Iran
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Ectopic adrenal tissue is a rare condition associated with embryological development defects seen in many different areas in the abdomen and pelvis. Here, we aimed to discuss the clinicopathological features of ectopic adrenal tissues diagnosed in our clinic, in light of the literature. Methods: We included cases of ectopic adrenal tissues incidentally detected in the specimens from patients undergoing operation for various diagnoses during 2012- March 2020. The cases were examined according to gender, age, location and accompanying pathological diagnoses. During this period, 15 cases of ectopic adrenal tissues (6 paratubal, 3 paraovarian, 2 paratesticular, 1 spermatic cord, 1 paraaortic, 1 liver capsule, 1 omentum) were detected accompanied by two endometrial carcinomas, two serous cystadenomas, one seminoma, one mixed germ cell tumor, one bilateral ovarian serous carcinoma and hepatic high-grade colon adenocarcinoma metastasis. Results: In this report, the fifth ectopic adrenal tissue accompanying a malignant testicular tumor, the fifth and sixth ectopic adrenal tissues occurring with ovarian serous cystadenoma, the first case observed with serous cystadenocarcinoma and the first case detected with hepatic adenocarcinoma metastasis are presented. Our cases are mostly women and adult men. Conclusion: Ectopic adrenal tissues can lead to hormonal problems and also to adrenal cortex and medulla neoplasms. Microscopically, they may be confused with clear cell gynecological and germ cell tumors. If the ectopic focus is misdiagnosed as an implant, a benign entity may be incorrectly reported as malignant. Also, it is important to prevent mis-staging in malignancies. For precise diagnosis, an immunopanel such as inhibin, melan A, and calretinin can be performed.
Açıklama
Anahtar Kelimeler
Clear Cell Tumors, Ectopic Adrenal, Ovarian Tumor, Testicular Neoplasms
Kaynak
Archives of Iranian Medicine
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
34
Sayı
4
Künye
Sensu, S., Keser, S. H., Gurbuz, Y., Barisik, N. O., & Gul, A. E. (2021). Clinicopathological Evaluation of 15 Ectopic Adrenal Tissues. Archives of Iranian Medicine, 24(4), 301-305.