Clinicopathological evaluation of 15 Ectopic adrenal tissues

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dc.authoridSibel Şensu / 0000-0002-4607-780Xen_US
dc.authoridYeşim Saliha Gürbüz / 0000-0002-4278-8241en_US
dc.authorscopusidSibel Şensu / 35746731800
dc.authorscopusidYeşim Saliha Gürbüz / 7004052030
dc.authorwosidSibel Şensu / AGU-9782-2022
dc.authorwosidYeşim Gürbüz / CRQ-9252-2022
dc.contributor.authorŞensu, Sibel
dc.contributor.authorKeser, Sevinç Hallaç
dc.contributor.authorGürbüz, Yeşim Saliha
dc.contributor.authorBarışık, Nagehan Özdemir
dc.contributor.authorGül, Aylin Ege
dc.date.accessioned2021-06-24T12:06:59Z
dc.date.available2021-06-24T12:06:59Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Ectopic adrenal tissue is a rare condition associated with embryological development defects seen in many different areas in the abdomen and pelvis. Here, we aimed to discuss the clinicopathological features of ectopic adrenal tissues diagnosed in our clinic, in light of the literature. Methods: We included cases of ectopic adrenal tissues incidentally detected in the specimens from patients undergoing operation for various diagnoses during 2012- March 2020. The cases were examined according to gender, age, location and accompanying pathological diagnoses. During this period, 15 cases of ectopic adrenal tissues (6 paratubal, 3 paraovarian, 2 paratesticular, 1 spermatic cord, 1 paraaortic, 1 liver capsule, 1 omentum) were detected accompanied by two endometrial carcinomas, two serous cystadenomas, one seminoma, one mixed germ cell tumor, one bilateral ovarian serous carcinoma and hepatic high-grade colon adenocarcinoma metastasis. Results: In this report, the fifth ectopic adrenal tissue accompanying a malignant testicular tumor, the fifth and sixth ectopic adrenal tissues occurring with ovarian serous cystadenoma, the first case observed with serous cystadenocarcinoma and the first case detected with hepatic adenocarcinoma metastasis are presented. Our cases are mostly women and adult men. Conclusion: Ectopic adrenal tissues can lead to hormonal problems and also to adrenal cortex and medulla neoplasms. Microscopically, they may be confused with clear cell gynecological and germ cell tumors. If the ectopic focus is misdiagnosed as an implant, a benign entity may be incorrectly reported as malignant. Also, it is important to prevent mis-staging in malignancies. For precise diagnosis, an immunopanel such as inhibin, melan A, and calretinin can be performed.en_US
dc.identifier.citationSensu, S., Keser, S. H., Gurbuz, Y., Barisik, N. O., & Gul, A. E. (2021). Clinicopathological Evaluation of 15 Ectopic Adrenal Tissues. Archives of Iranian Medicine, 24(4), 301-305.en_US
dc.identifier.doi10.34172/AIM.2021.42en_US
dc.identifier.endpage305en_US
dc.identifier.issn1029-2977en_US
dc.identifier.issue4en_US
dc.identifier.pmid34196190en_US
dc.identifier.scopus2-s2.0-85108090469en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage301en_US
dc.identifier.urihttps://doi.org/10.34172/AIM.2021.42
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1832
dc.identifier.volume34en_US
dc.identifier.wosWOS:000674176500005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorŞensu, Sibel
dc.institutionauthorGürbüz, Yeşim Saliha
dc.language.isoenen_US
dc.publisherAcademy of Medical Sciences of I.R. Iranen_US
dc.relation.ispartofArchives of Iranian Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectClear Cell Tumorsen_US
dc.subjectEctopic Adrenalen_US
dc.subjectOvarian Tumoren_US
dc.subjectTesticular Neoplasmsen_US
dc.titleClinicopathological evaluation of 15 Ectopic adrenal tissuesen_US
dc.typeArticleen_US

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