Changes in HOMA-IR index levels after bariatric surgery: Comparison of single anastomosis duodenal switch-proximal approach (SADS-p) and one anastomosis gastric bypass-mini gastric bypass (OAGB-MGB)
Yükleniyor...
Dosyalar
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Bariatric surgery plays a major role in ameliorating metabolic abnormalities of type 2 diabetes (T2DM). The aim of this study was to evaluate the early effects of “Single Anastomosis Duodenal Switch-proximal approach” (SADS-p) and “One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB) on the “homeostasis model assessment of insulin resistance” (HOMA-IR) index levels in morbidly obese patients with T2DM. Methods: In this retrospective 3-year trial, outcomes of SADS-p and OAGB-MGB patients were compared considering the changes in HOMA-IR index levels. All bariatric procedures were performed by a single primary surgeon recognized as a surgeon of excellence by IFSO-EC with the assistance of one or two additional attending surgeons. SADS-p was performed on 60(10 males) patients, and 200(27 males) patients underwent OAGB-MGB. Forty-six patients (78%) in the SADS-p group and 125 (63%) in the OAGB-MGB group had T2DM. Patients were evaluated before surgery and 1,3,9,12 months after surgery. Results: In both groups, the HOMA-IR index levels decreased significantly after surgery (p < 0.05), and both procedures markedly improved glycemic control. In the SADS-p group the HOMA-IR index levels significantly decreased from 6.2 to 1.4 after the 12th month of surgery (p < 0.05), in OAGB-MGB group HOMA-IR index levels significantly decreased from 5,9 to 1.7 after the 12th month of surgery (p < 0.05). Conclusion: Both procedures are promising operations which offer excellent control on weight, HOMA-IR index and diabetes. © 2020 IJS Publishing Group Ltd
Açıklama
Anahtar Kelimeler
Bariatric Surgery, Diabetes, Homa-Ir, Insulin, Metabolic Surgery, Morbid Obesity, Oagb-Mgb, One Anastomosis Gastric Bypass-Mini Gastric Bypass, Robotic Gastric Bypass, Single Anastomosis Duodenal Switch-Proximal Approach, Type 2 Diabetes, Weight Loss
Kaynak
International Journal of Surgery
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
78
Sayı
Künye
Ozmen, M. M., Guldogan, C. E., & Gundogdu, E. (2020). Changes in HOMA-IR Index Levels After Bariatric Surgery: Comparison of Single Anastomosis Duodenal Switch-proximal approach (SADS-p) and One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB). International Journal of Surgery.
