Changes in HOMA-IR index levels after bariatric surgery: Comparison of single anastomosis duodenal switch-proximal approach (SADS-p) and one anastomosis gastric bypass-mini gastric bypass (OAGB-MGB)

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dc.authoridMehmet Mahir Özmen / 0000-0003-0649-0111
dc.authoridCem Emir Güldoğan / 0000-0003-0634-5619
dc.authoridEmre Gündoğdu / 0000-0002-2756-1372
dc.authorscopusidMehmet Mahir Özmen / 57211511111
dc.authorscopusidCem Emir Güldoğan / 55890565600
dc.authorscopusidEmre Gündoğdu / 36165504700
dc.authorwosidMehmet Mahir Özmen / AAO-2321-2020
dc.authorwosidCem Emir Güldoğan / K-3824-2016
dc.authorwosidEmre Gündoğdu / AAR-6328-2020
dc.contributor.authorÖzmen, Mehmet Mahir
dc.contributor.authorGüldoğan, Cem Emir
dc.contributor.authorGündoğdu, Emre
dc.date.accessioned2020-08-30T20:01:33Z
dc.date.available2020-08-30T20:01:33Z
dc.date.issued2020
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Bariatric surgery plays a major role in ameliorating metabolic abnormalities of type 2 diabetes (T2DM). The aim of this study was to evaluate the early effects of “Single Anastomosis Duodenal Switch-proximal approach” (SADS-p) and “One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB) on the “homeostasis model assessment of insulin resistance” (HOMA-IR) index levels in morbidly obese patients with T2DM. Methods: In this retrospective 3-year trial, outcomes of SADS-p and OAGB-MGB patients were compared considering the changes in HOMA-IR index levels. All bariatric procedures were performed by a single primary surgeon recognized as a surgeon of excellence by IFSO-EC with the assistance of one or two additional attending surgeons. SADS-p was performed on 60(10 males) patients, and 200(27 males) patients underwent OAGB-MGB. Forty-six patients (78%) in the SADS-p group and 125 (63%) in the OAGB-MGB group had T2DM. Patients were evaluated before surgery and 1,3,9,12 months after surgery. Results: In both groups, the HOMA-IR index levels decreased significantly after surgery (p < 0.05), and both procedures markedly improved glycemic control. In the SADS-p group the HOMA-IR index levels significantly decreased from 6.2 to 1.4 after the 12th month of surgery (p < 0.05), in OAGB-MGB group HOMA-IR index levels significantly decreased from 5,9 to 1.7 after the 12th month of surgery (p < 0.05). Conclusion: Both procedures are promising operations which offer excellent control on weight, HOMA-IR index and diabetes. © 2020 IJS Publishing Group Ltden_US
dc.identifier.citationOzmen, M. M., Guldogan, C. E., & Gundogdu, E. (2020). Changes in HOMA-IR Index Levels After Bariatric Surgery: Comparison of Single Anastomosis Duodenal Switch-proximal approach (SADS-p) and One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB). International Journal of Surgery.en_US
dc.identifier.doi10.1016/j.ijsu.2020.04.008en_US
dc.identifier.endpage41en_US
dc.identifier.issn1743-9191en_US
dc.identifier.pmid32305534en_US
dc.identifier.scopus2-s2.0-85083528782en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage36en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijsu.2020.04.008
dc.identifier.urihttps://hdl.handle.net/20.500.12713/282
dc.identifier.volume78en_US
dc.identifier.wosWOS:000539259900016en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzmen, Mehmet Mahiren_US
dc.institutionauthorGüldoğan, Cem Emiren_US
dc.institutionauthorGündoğdu, Emreen_US
dc.language.isoenen_US
dc.publisherElsevier Ltden_US
dc.relation.ispartofInternational Journal of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBariatric Surgeryen_US
dc.subjectDiabetesen_US
dc.subjectHoma-Iren_US
dc.subjectInsulinen_US
dc.subjectMetabolic Surgeryen_US
dc.subjectMorbid Obesityen_US
dc.subjectOagb-Mgben_US
dc.subjectOne Anastomosis Gastric Bypass-Mini Gastric Bypassen_US
dc.subjectRobotic Gastric Bypassen_US
dc.subjectSingle Anastomosis Duodenal Switch-Proximal Approachen_US
dc.subjectType 2 Diabetesen_US
dc.subjectWeight Lossen_US
dc.titleChanges in HOMA-IR index levels after bariatric surgery: Comparison of single anastomosis duodenal switch-proximal approach (SADS-p) and one anastomosis gastric bypass-mini gastric bypass (OAGB-MGB)en_US
dc.typeArticleen_US

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