A rare lymphoproliferative disease: castleman disease
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
GALENOS YAYINCILIK
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Castleman disease is a rare lymphoproliferative disease also known as angiofollicular lymph node hyperplasia. It is classified as hyaline vascular and plasmacytic variants histologically but characteristics of both types can coexist. Most unicentric cases of the disease are hyaline vascular while most multicentric cases are of the plasmacytic type. Although the pathogenesis is not completely understood, the role of interleukin (IL)-6 in unicentric disease and the roles of IL-6 and human herpes virus-8 in multicentric disease are well defined. Unicentric disease is typically localized and symptoms are minimal and treated locally. Multicentric disease is systemic and clinically characterized by generalized lymphadenopathy, splenomegaly, anemia, and systemic inflammatory symptoms. Systemic therapies are primarily given. Several malignant diseases including lymphomas, POEMS syndrome, follicular dendritic cell sarcomas, paraneoplastic pemphigus, Kaposi sarcoma, and amyloidosis can be associated with Castleman disease. In this paper, recent information about Castleman disease, which is a rare disease, is summarized.
Açıklama
Anahtar Kelimeler
Castleman Disease, Diagnosis, Treatment
Kaynak
TURKISH JOURNAL OF HEMATOLOGY
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
38
Sayı
4
Künye
Gündüz, E., Özdemir, N., Bakanay, Ş. M., & Karakuş, S. (2021). A Rare Lymphoproliferative Disease: Castleman Disease. Turkish Journal of Hematology, 38(4), 314.
