A rare lymphoproliferative disease: castleman disease

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dc.authoridGül Nihal Özdemir / 0000-0002-3204-4353en_US
dc.authorscopusidGül Nihal Özdemir / 34067792800
dc.authorwosidGül Nihal Özdemir / AAO-9962-2020
dc.contributor.authorGündüz, Eren
dc.contributor.authorÖzdemir, Gül Nihal
dc.contributor.authorBakanay, Şule Mine
dc.contributor.authorKarakuş, Sema
dc.date.accessioned2021-12-28T11:18:10Z
dc.date.available2021-12-28T11:18:10Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractCastleman disease is a rare lymphoproliferative disease also known as angiofollicular lymph node hyperplasia. It is classified as hyaline vascular and plasmacytic variants histologically but characteristics of both types can coexist. Most unicentric cases of the disease are hyaline vascular while most multicentric cases are of the plasmacytic type. Although the pathogenesis is not completely understood, the role of interleukin (IL)-6 in unicentric disease and the roles of IL-6 and human herpes virus-8 in multicentric disease are well defined. Unicentric disease is typically localized and symptoms are minimal and treated locally. Multicentric disease is systemic and clinically characterized by generalized lymphadenopathy, splenomegaly, anemia, and systemic inflammatory symptoms. Systemic therapies are primarily given. Several malignant diseases including lymphomas, POEMS syndrome, follicular dendritic cell sarcomas, paraneoplastic pemphigus, Kaposi sarcoma, and amyloidosis can be associated with Castleman disease. In this paper, recent information about Castleman disease, which is a rare disease, is summarized.en_US
dc.identifier.citationGündüz, E., Özdemir, N., Bakanay, Ş. M., & Karakuş, S. (2021). A Rare Lymphoproliferative Disease: Castleman Disease. Turkish Journal of Hematology, 38(4), 314.en_US
dc.identifier.doi10.4274/tjh.galenos.2021.2021.0440en_US
dc.identifier.endpage320en_US
dc.identifier.issn1300-7777en_US
dc.identifier.issn1308-5263en_US
dc.identifier.issue4en_US
dc.identifier.pmid34719151en_US
dc.identifier.scopus2-s2.0-85122057704en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage314en_US
dc.identifier.urihttps://doi.org/10.4274/tjh.galenos.2021.2021.0440
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2362
dc.identifier.volume38en_US
dc.identifier.wosWOS:000730491500007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzdemir, Gül Nihal
dc.language.isoenen_US
dc.publisherGALENOS YAYINCILIKen_US
dc.relation.ispartofTURKISH JOURNAL OF HEMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCastleman Diseaseen_US
dc.subjectDiagnosisen_US
dc.subjectTreatmenten_US
dc.titleA rare lymphoproliferative disease: castleman diseaseen_US
dc.typeArticleen_US

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