High C-reactive protein level as a predictor for appendiceal perforation

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dc.authoridÖmer Vefik Özozan / 0000-0001-5885-7865en_US
dc.authorscopusidÖmer Vefik Özozan / 20434255000
dc.authorwosidÖmer Vefik Özozan / AAU-4795-2020
dc.contributor.authorÖzozan, Ömer Vefik
dc.contributor.authorVural, Veli
dc.date.accessioned2020-08-30T20:06:23Z
dc.date.available2020-08-30T20:06:23Z
dc.date.issued2020
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBACKGROUND: Between 18% and 34% of acute appendicitis (AA) patients may have complicated appendicitis. Perforation is the most important complication of AA. Perforation increases morbidity and mortality. In this study, we aimed to investigate the role of basic inflammatory markers in the diagnosis of perforated AA. METHODS: A retrospective chart review was conducted of patients who underwent appendectomy with a diagnosis of AA between January 2014 and October 2019 at Akdeniz University Faculty of Medicine; and between December 2017 and October 2019 at lstinye University Faculty of Medicine Hospital. Markers recorded were as follows: white blood cell count, neutrophils, lymphocytes, platelets, c-reactive protein, mean platelet volume, red cell distribution width and eosinophils. Hematological indices were combined to generate the following three ratios: white cell neutrophil ratio, platelet lymphocyte ratio and neutrophil-lymphocyte ratio. RESULT: A total of 536 patients with a diagnosis of AA underwent an operation. There were 344 (64.1%) male patients and 192 (35.9%) female patients. The mean age of the patients was 36.7 +/- 16.2 (15-88) years. There were 94 (17.5%) patients with perforated AA and 442 (82.5%) patients with non-perforated AA. C-reactive protein (AUC: 0.81, p<0.00 I) was the most accurate markers in distinguishing the perforated and non-perforated group. CONCLUSION: Elevated CRP level is a nonspecific inflammatory marker in most of the inflammatory diseases. A high CRP level can, therefore, be used as a supplement in the diagnosis of perforated AA.en_US
dc.identifier.citationOzozan, O. V., & Vural, V. (2020). High C-reactive protein level as a predictor for appendiceal perforation. ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, 26(1), 63–66. https://doi.org/10.14744/tjtes.2019.14799en_US
dc.identifier.doi10.14744/tjtes.2019.14799en_US
dc.identifier.endpage66en_US
dc.identifier.issn1306-696Xen_US
dc.identifier.issue1en_US
dc.identifier.pmid31942732en_US
dc.identifier.scopus2-s2.0-85077941475en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage63en_US
dc.identifier.trdizinid374995en_US
dc.identifier.urihttps://doi.org/10.14744/tjtes.2019.14799
dc.identifier.urihttps://hdl.handle.net/20.500.12713/496
dc.identifier.volume26en_US
dc.identifier.wosWOS:000507495500010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzozan, Ömer Vefiken_US
dc.language.isoenen_US
dc.publisherTurkish Assoc Trauma Emergency Surgeryen_US
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAppendicitisen_US
dc.subjectC-Reactive Proteinen_US
dc.subjectPerforationen_US
dc.titleHigh C-reactive protein level as a predictor for appendiceal perforationen_US
dc.typeArticleen_US

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